The prognostic value of multilineage dysplasia in de novo acute myeloid leukemia patients with intermediate-risk cytogenetics is dependent on NPM1 mutational status

被引:37
作者
Diaz-Beya, Marina
Rozman, Maria [1 ]
Pratcorona, Marta [1 ]
Torrebadell, Montserrat [1 ]
Camos, Mireia [1 ]
Aguilar, Joseph L. I.
Esteve, Jordi [1 ]
机构
[1] Hosp Clin Barcelona, Dept Hematol, IDIBAPS, Hematopathol Unit, E-08036 Barcelona, Spain
关键词
CLASSIFICATION; AML; RELEVANCE; IMPACT;
D O I
10.1182/blood-2010-09-307314
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:6147 / 6148
页数:4
相关论文
共 6 条
[1]  
[Anonymous], 2008, WHO CLASSIFICATION T
[2]   Prognostic impact of acute myeloid leukemia classification - Importance of detection of recurring cytogenetic abnormalities and multilineage dysplasia on survival [J].
Arber, DA ;
Stein, AS ;
Carter, NH ;
Ikle, D ;
Forman, SJ ;
Slovak, ML .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2003, 119 (05) :672-680
[3]   Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1) [J].
Falini, Brunangelo ;
Macijewski, Katja ;
Weiss, Tamara ;
Bacher, Ulrike ;
Schnittger, Susanne ;
Kern, Wolfgang ;
Kohlmann, Alexander ;
Klein, Hans-Ulrich ;
Vignetti, Marco ;
Piciocchi, Alfonso ;
Fazi, Paola ;
Martelli, Maria Paola ;
Vitale, Antonella ;
Pileri, Stefano ;
Miesner, Miriam ;
Santucci, Antonella ;
Haferlach, Claudia ;
Mandelli, Franco ;
Haferlach, Torsten .
BLOOD, 2010, 115 (18) :3776-3786
[4]   Morphologic dysplasia in de novo acute myeloid leukemia (AML) is related to unfavorable cytogenetics but has no independent prognostic relevance under the conditions of intensive induction therapy:: Results of a multiparameter analysis from the German AML cooperative group studies [J].
Haferlach, T ;
Schoch, C ;
Löffler, H ;
Gassmann, W ;
Kern, W ;
Schnittger, S ;
Fonatsch, C ;
Ludwig, WD ;
Wuchter, C ;
Schlegelberger, B ;
Staib, P ;
Reichle, A ;
Kubica, U ;
Eimermacher, H ;
Balleisen, L ;
Grüneisen, A ;
Haase, D ;
Aul, C ;
Karow, J ;
Lengfelder, E ;
Wörmann, B ;
Heinecke, A ;
Sauerland, MC ;
Büchner, T ;
Hiddemann, W .
JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (02) :256-265
[5]   MLF according to the WHO classification in AML has no correlation with age and no independent prognostic relevance as analyzed in 1766 patients [J].
Wandt, Hannes ;
Schakel, Ulrike ;
Kroschinsky, Frank ;
Prange-Krex, Gabriele ;
Mohr, Brigitte ;
Thiede, Christian ;
Pascheberg, Ulrich ;
Soucek, Silke ;
Schaich, Markus ;
Ehninger, Gerhard .
BLOOD, 2008, 111 (04) :1855-1861
[6]   Clinical characterization of acute myeloid leukemia with myelodysplasia-related changes as defined by the 2008 WHO classification system [J].
Weinberg, Olga K. ;
Seetharam, Mahesh ;
Ren, Li ;
Seo, Katie ;
Ma, Lisa ;
Merker, Jason D. ;
Gotlib, Jason ;
Zehnder, James L. ;
Arber, Daniel A. .
BLOOD, 2009, 113 (09) :1906-1908