Treatment of immune thrombocytopenia with eltrombopag in patients who had and who had not received prior rituximab: post-hoc analysis of the EXTEND study

被引：1

作者：

Meyer, Oliver ^{[1
]}

Wong, Raymond S. M. ^{[2
]}

Khelif, Abderrahim ^{[3
]}

Stankovic, Miona ^{[4
]}

Maier, Joan ^{[4
]}

Saleh, Mansoor N. ^{[5
]}

Bussel, James B. ^{[6
]}

机构：

[1] Charite Univ Med Berlin, Inst Transfus Med, Berlin, Germany

[2] Chinese Univ Hong Kong, Sir YK Pao Ctr Canc, Dept Med & Therapeut, Hong Kong, Peoples R China

[3] Univ Sousse, Hop Univ Farhat Hached, Sousse, Tunisia

[4] Novartis Pharma AG, Basel, Switzerland

[5] Univ Alabama Birmingham, ONeal Comprehens Canc Ctr, Birmingham, AL USA

[6] Weill Cornell Med, Div Pediat Hematol Oncol, New York, NY USA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2022年 / 196卷 / 02期

关键词：

eltrombopag; efficacy; immune thrombocytopenia; rituximab; safety; DOUBLE-BLIND; LONG-TERM; EFFICACY; MANAGEMENT; PURPURA; SAFETY;

D O I：

10.1111/bjh.17800

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：448 / 452

页数：5

共 11 条

[1] Fostamatinib for the treatment of adult persistent and chronic immune thrombocytopenia: Results of two phase 3, randomized, placebo-controlled trials [J].

Bussel, James ;

Arnold, Donald M. ;

Grossbard, Elliot ;

Mayer, Jiri ;

Trelinski, Jacek ;

Homenda, Wojciech ;

Hellmann, Andrzej ;

Windyga, Jerzy ;

Sivcheva, Liliya ;

Khalafallah, Alhossain A. ;

Zaja, Francesco ;

Cooper, Nichola ;

Markovtsov, Vadim ;

Zayed, Hany ;

Duliege, Anne-Marie .

AMERICAN JOURNAL OF HEMATOLOGY, 2018, 93 (07) :921-930

[2] Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura [J].

Bussel, James B. ;

Cheng, Gregory ;

Saleh, Mansoor N. ;

Psaila, Bethan ;

Kovaleva, Lidia ;

Meddeb, Balkis ;

Kloczko, Janusz ;

Hassani, Habib ;

Mayer, Bhabita ;

Stone, Nicole L. ;

Arning, Michael ;

Provan, Drew ;

Jenkins, Julian M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (22) :2237-2247

[3] Repeated short-term use of eltrombopag in patients with chronic immune thrombocytopenia (ITP) [J].

Bussel, James B. ;

Saleh, Mansoor N. ;

Vasey, Sandra Y. ;

Mayer, Bhabita ;

Arning, Michael ;

Stone, Nicole L. .

BRITISH JOURNAL OF HAEMATOLOGY, 2013, 160 (04) :538-546

[4] Effect of eltrombopag on platelet counts and bleeding during treatment of chronic idiopathic thrombocytopenic purpura: a randomised, double-blind, placebo-controlled trial [J].

Bussel, James B. ;

Provan, Drew ;

Shamsi, Tahir ;

Cheng, Gregory ;

Psaila, Bethan ;

Kovaleva, Lidia ;

Salama, Abdulgabar ;

Jenkins, Julian M. ;

Roychowdhury, Debasish ;

Mayer, Bhabita ;

Stone, Nicole ;

Arning, Michael .

LANCET, 2009, 373 (9664) :641-648

[5] Eltrombopag for management of chronic immune thrombocytopenia (RAISE): a 6-month, randomised, phase 3 study [J].

Cheng, Gregory ;

Saleh, Mansoor N. ;

Marcher, Claus ;

Vasey, Sandra ;

Mayer, Bhabita ;

Aivado, Manuel ;

Arning, Michael ;

Stone, Nicole L. ;

Bussel, James B. .

LANCET, 2011, 377 (9763) :393-402

[6] Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura:: a double-blind randomised controlled trial [J].

Kuter, David J. ;

Bussel, James B. ;

Lyons, Roger M. ;

Pullarkat, Vinod ;

Gernsheimer, Terry B. ;

Senecal, Francis M. ;

Aledort, Louis M. ;

George, James N. ;

Kessler, Craig M. ;

Sanz, Miguel A. ;

Liebman, Howard A. ;

Slovick, Frank T. ;

de Wolf, J. Th M. ;

Bourgeois, Emmanuelle ;

Guthrie, Troy H., Jr. ;

Newland, Adrian ;

Wasser, Jeffrey S. ;

Hamburg, Solomon I. ;

Grande, Carlos ;

Lefrere, Francois ;

Lichtin, Alan Eli ;

Tarantino, Michael D. ;

Terebelo, Howard R. ;

Viallard, Jean-Francois ;

Cuevas, Francis J. ;

Go, Ronald S. ;

Henry, David H. ;

Redner, Robert L. ;

Rice, Lawrence ;

Schipperus, Martin R. ;

Guo, D. Matthew ;

Nichol, Janet L. .

LANCET, 2008, 371 (9610) :395-403

[7] American Society of Hematology 2019 guidelines for immune thrombocytopenia [J].

Neunert, Cindy ;

Terrell, Deirdra R. ;

Arnold, Donald M. ;

Buchanan, George ;

Cines, Douglas B. ;

Cooper, Nichola ;

Cuker, Adam ;

Despotovic, Jenny M. ;

George, James N. ;

Grace, Rachael F. ;

Kuehne, Thomas ;

Kuter, David J. ;

Lim, Wendy ;

McCrae, Keith R. ;

Pruitt, Barbara ;

Shimanek, Hayley ;

Vesely, Sara K. .

BLOOD ADVANCES, 2019, 3 (23) :3829-3866

[8]

Novartis Europharm Limited, 2021, REV ELTR SUMM PROD C

[9] Updated international consensus report on the investigation and management of primary immune thrombocytopenia [J].

Provan, Drew ;

Arnold, Donald M. ;

Bussel, James B. ;

Chong, Beng H. ;

Cooper, Nichola ;

Gernsheimer, Terry ;

Ghanima, Waleed ;

Godeau, Bertrand ;

Jose Gonzalez-Lopez, Tomas ;

Grainger, John ;

Hou, Ming ;

Kruse, Caroline ;

McDonald, Vickie ;

Michel, Marc ;

Newland, Adrian C. ;

Pavord, Sue ;

Rodeghiero, Francesco ;

Scully, Marie ;

Tomiyama, Yoshiaki ;

Wong, Raymond S. ;

Zaja, Francesco ;

Kuter, David J. .

BLOOD ADVANCES, 2019, 3 (22) :3780-3817

[10] Safety and efficacy of eltrombopag for treatment of chronic immune thrombocytopenia: results of the long-term, open-label EXTEND study [J].

Saleh, Mansoor N. ;

Bussel, James B. ;

Cheng, Gregory ;

Meyer, Oliver ;

Bailey, Christine K. ;

Arning, Michael ;

Brainsky, Andres .

BLOOD, 2013, 121 (03) :537-545

← 1 2 →