Formation of mammalian oocytes and their growth, differentiation and maturation within ovarian follicles

被引:240
作者
van den Hurk, R
Zhao, H
机构
[1] Univ Utrecht, Fac Vet Med, Dept Farm Anim Hlth, NL-3508 TD Utrecht, Netherlands
[2] NV Organon, Sect Fertil & Contracept, Dept Pharmacol R&D, NL-5340 BH Oss, Netherlands
关键词
ovaries; oocytes; follicles; hormones; growth factors;
D O I
10.1016/j.theriogenology.2004.08.005
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The limited knowledge on the regulation of oocyte formation, the different steps of folliculogenesis and the required conditions for oocytes to undergo proper growth, differentiation and maturation are major causes of the failure in obtaining viable offspring from in vitro cultured early oocytes from domestic animals and humans. This review highlights the factors that at present are known to be involved in the formation of mammalian oocytes and their growth, differentiation and maturation within ovarian follicles. (c) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:1717 / 1751
页数:35
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