Evidence for a melanin cell wall component in Pneumocystis carinii

被引:11
|
作者
Icenhour, CR
Kottom, TJ
Limper, AH
机构
[1] Mayo Clin, Div Pulm Crit Care & Internal Med, Thorac Dis Res Unit, Rochester, MN 55905 USA
[2] Mayo Clin & Mayo Fdn, Dept Biochem & Mol Biol, Rochester, MN 55905 USA
关键词
D O I
10.1128/IAI.71.9.5360-5363.2003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Fluorescein isothiocyanate-labeled monoclonal antibodies specific for fungal melanin were used in this study to visualize melanin-like components of the Pneumocystis carinii cell wall. A colorimetric enzyme assay confirmed these findings. This is the first report of melanin-like pigments in Pneumocystis.
引用
收藏
页码:5360 / 5363
页数:4
相关论文
共 50 条
  • [1] Evidence for Proinflammatory β-1,6 Glucans in the Pneumocystis carinii Cell Wall
    Kottom, Theodore J.
    Hebrink, Deanne M.
    Jenson, Paige E.
    Gudmundsson, Gunnar
    Limper, Andrew H.
    INFECTION AND IMMUNITY, 2015, 83 (07) : 2816 - 2826
  • [2] Melanin-like pigments in Pneumocystis carinii
    Icenhour, CR
    Kottom, TJ
    Limper, AH
    JOURNAL OF EUKARYOTIC MICROBIOLOGY, 2003, 50 : 621 - 621
  • [3] ULTRASTRUCTURAL EVIDENCE OF A PORE IN THE CYST WALL OF PNEUMOCYSTIS-CARINII
    ITATANI, C
    WU, T
    MICROSCOPY RESEARCH AND TECHNIQUE, 1994, 29 (06) : 493 - 493
  • [4] Evidence For β-1,6 Glucans With Pro-Inflammatory Activity In The Pneumocystis Carinii Cell Wall
    Limper, A. H.
    Hebrink, D.
    Kottom, T. J.
    Iqbal, S.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 187
  • [5] Pneumocystis carinii:: Cell wall β-glucan-mediated pulmonary inflammation
    Limper, AH
    Lebron, F
    Evans, SE
    Hahn, RY
    JOURNAL OF EUKARYOTIC MICROBIOLOGY, 2003, 50 : 646 - 646
  • [6] Semisynthetic echinocandins affect cell wall deposition of Pneumocystis carinii in vitro and in vivo
    Bartlett, MS
    Current, WL
    Goheen, MP
    Boylan, CJ
    Lee, CH
    Shaw, MM
    Queener, SF
    Smith, JW
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (08) : 1811 - 1816
  • [7] A CYST-SPECIFIC COMPONENT OF PNEUMOCYSTIS-CARINII
    TANABE, K
    SATO, A
    PARASITOLOGY RESEARCH, 1990, 76 (07): : 633 - 634
  • [8] YEAST GLUCAN IN THE CYST WALL OF PNEUMOCYSTIS-CARINII
    MATSUMOTO, Y
    MATSUDA, S
    TEGOSHI, T
    JOURNAL OF PROTOZOOLOGY, 1989, 36 (01): : S21 - S22
  • [9] Cell wall antigens of Pneumocystis carinii trophozoites and cysts:: Purification and carbohydrate analysis of these glycoproteins
    De Stefano, JA
    Myers, JD
    Du Pont, D
    Foy, JM
    Theus, SA
    Walzer, PD
    JOURNAL OF EUKARYOTIC MICROBIOLOGY, 1998, 45 (03) : 334 - 343
  • [10] PNEUMOCYSTIS CARINII
    HAMLIN, WB
    JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1968, 204 (02): : 173 - &