Matching SOCS with function

被引:54
作者
Johnston, JA [1 ]
O'Shea, JJ
机构
[1] Queens Univ Belfast, Dept Immunol, Belfast, Antrim, North Ireland
[2] NIAMSD, Mol Immunol & Inflammat Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1038/ni0603-507
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Overexpression studies suggest that SOCS3 is a pleiotropic negative regulator of cytokines. The generation of Socs3(-/-) mice indicates that SOCS3 actually functions in a remarkably specific manner.
引用
收藏
页码:507 / 509
页数:3
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