Initial Combination Therapy with Adalimumab Plus Methotrexate Leads to Better Long-Term Outcomes Than with Either Monotherapy in Patients with Early Rheumatoid Arthritis: 8-Year Results of An Open-Label Extension of a Phase 3 Trial

被引:0
|
作者
Breedveld, Ferdinand C. [1 ]
Keystone, Edward [2 ]
van der Heijde, Desiree [1 ]
Landewe, Robert [3 ]
Smolen, Josef [4 ,5 ]
Guerette, Benoit [6 ]
McIlraith, Melissa [6 ]
Kupper, Hartmut [7 ]
Liu, Shufang [8 ]
Wolfe, Benjamin [8 ]
Kavanaugh, Arthur [9 ]
机构
[1] Leiden Univ, Med Ctr, Leiden, Netherlands
[2] Univ Toronto, Toronto, ON, Canada
[3] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands
[4] Med Univ Vienna, Vienna, Austria
[5] Hietzing Hosp, Vienna, Austria
[6] Abbott, Rungis, France
[7] Abbott GmbH & Co KG, Ludwigshafen, Germany
[8] Abbott, Abbott Pk, IL USA
[9] Univ Calif San Diego, San Diego, CA 92103 USA
来源
ARTHRITIS AND RHEUMATISM | 2011年 / 63卷 / 10期
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1231
引用
收藏
页码:S481 / S481
页数:1
相关论文
共 50 条
  • [31] Long-Term Safety and Efficacy of Voxelotor for Patients with Sickle Cell Disease: Results from an Open-Label Extension of the Phase 3 HOPE Trial
    Achebe, Maureen
    Hassab, Hoda
    Alkindi, Salam
    Brown, R. Clark Clark
    Telfer, Paul
    Biemond, Bart J.
    Gordeuk, Victor R.
    Lipato, Thokozeni
    Tonda, Margaret
    Gray, Sarah
    Howard, Joanna
    BLOOD, 2021, 138
  • [32] Correlations Between Early MRI Parameters and Long-Term Clinical Outcomes in Phase 3 and Open-Label Extension Studies of Ozanimod in Relapsing Multiple Sclerosis: Final Results From the DAYBREAK Open-label Extension Study
    Arnold, Douglas
    Freeman, Leorah
    Hartung, Hans-Peter
    Montalban, Xavier
    Cohen, Jeffrey
    Bar-Or, Amit
    Steinman, Lawrence
    DeLuca, John
    Sheffield, James
    Cheng, Chun-Yen
    Riolo, Jon
    Pachai, Chahin
    Cree, Bruce A. C.
    MULTIPLE SCLEROSIS JOURNAL, 2024, 30 (03) : 1050 - 1051
  • [33] Efficacy and safety of nateglinide plus sitagliptin combination therapy in type 2 diabetes patients inadequately controlled by sitagliptin monotherapy: a phase 3, multicenter, open-label, long-term study
    Hirose T.
    Saitoh C.
    Oikawa I.
    Kondo N.
    Diabetology International, 2018, 9 (3) : 168 - 178
  • [34] Certolizumab pegol plus methotrexate 5-year results from the rheumatoid arthritis prevention of structural damage (RAPID) 2 randomized controlled trial and long-term extension in rheumatoid arthritis patients
    Smolen, Josef S.
    van Vollenhoven, Ronald
    Kavanaugh, Arthur
    Strand, Vibeke
    Vencovsky, Jiri
    Schiff, Michael
    Landewe, Robert
    Haraoui, Boulos
    Arendt, Catherine
    Mountian, Irina
    Carter, David
    van der Heijde, Desire
    ARTHRITIS RESEARCH & THERAPY, 2015, 17
  • [35] Long-Term Benefits of 4-Weekly Certolizumab Pegol Combination and Monotherapy On Household Productivity and Social Participation in Rheumatoid Arthritis: 5 Year Results from an Open Label Extension Study
    Strand, Vibeke
    Purcaru, Oana
    van Vollenhoven, Ronald F.
    Choy, Ernest
    Fleischmann, Roy
    ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : S567 - S567
  • [36] LONG-TERM BENEFITS OF 4-WEEKLY CERTOLIZUMAB PEGOL COMBINATION AND MONOTHERAPY ON HOUSEHOLD PRODUCTIVITY AND SOCIAL PARTICIPATION IN RHEUMATOID ARTHRITIS: 5 YEAR RESULTS FROM AN OPEN LABEL EXTENSION STUDY
    Strand, V
    Purcaru, O.
    Van Vollenhoven, R.
    Choy, E.
    Fleischmann, R.
    VALUE IN HEALTH, 2012, 15 (07) : A451 - A452
  • [37] Longterm Effect of Delaying Combination Therapy with Tumor Necrosis Factor Inhibitor in Patients with Aggressive Early Rheumatoid Arthritis: 10-year Efficacy and Safety of Adalimumab from the Randomized Controlled PREMIER Trial with Open-label Extension
    Keystone, Edward C.
    Breedveld, Ferdinand C.
    van der Heijde, Desiree
    Landewe, Robert
    Florentinus, Stefan
    Arulmani, Udayasankar
    Liu, Shufang
    Kupper, Hartmut
    Kavanaugh, Arthur
    JOURNAL OF RHEUMATOLOGY, 2014, 41 (01) : 5 - 14
  • [38] Long-Term Safety of Lacosamide as Adjunctive Therapy in Patients with Uncontrolled Partial-Onset Seizures: Results from a Phase III Open-Label Extension Trial
    Husain, Aatif
    Faught, Raymond Edward
    Chung, Steve
    Isojarvi, Jouko
    McShea, Cindy
    Doty, Pamela
    NEUROLOGY, 2011, 76 (09) : A291 - A291
  • [39] Long-Term (104-Week) Safety and Efficacy of Monotherapy with Apremilast in DMARD-Naive Patients with Psoriatic Arthritis: A Phase 3, Randomized, Controlled Trial and Open-Label Extension (PALACE 4)
    Wells, Alvin
    Edwards, Christopher
    Adebajo, Adewale O.
    Kivitz, Alan J.
    Bird, Paul
    Shah, Kamal
    Hu, ChiaChi
    Stevens, Randall M.
    Aelion, Jacob A.
    ARTHRITIS & RHEUMATOLOGY, 2014, 66 (12) : 3539 - 3539
  • [40] LONG-TERM (104-WEEK) EFFICACY AND SAFETY OF APREMILAST MONOTHERAPY IN DMARD-NAIVE PATIENTS WITH PSORIATIC ARTHRITIS: A PHASE 3, RANDOMIZED, CONTROLLED TRIAL AND OPEN-LABEL EXTENSION (PALACE 4)
    Wells, A.
    Edwards, C.
    Adebajo, A.
    Kivitz, A.
    Bird, P.
    Shah, K.
    Hu, C.
    Aelion, J.
    ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 : 863 - 864