Initial Combination Therapy with Adalimumab Plus Methotrexate Leads to Better Long-Term Outcomes Than with Either Monotherapy in Patients with Early Rheumatoid Arthritis: 8-Year Results of An Open-Label Extension of a Phase 3 Trial

被引:0
|
作者
Breedveld, Ferdinand C. [1 ]
Keystone, Edward [2 ]
van der Heijde, Desiree [1 ]
Landewe, Robert [3 ]
Smolen, Josef [4 ,5 ]
Guerette, Benoit [6 ]
McIlraith, Melissa [6 ]
Kupper, Hartmut [7 ]
Liu, Shufang [8 ]
Wolfe, Benjamin [8 ]
Kavanaugh, Arthur [9 ]
机构
[1] Leiden Univ, Med Ctr, Leiden, Netherlands
[2] Univ Toronto, Toronto, ON, Canada
[3] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands
[4] Med Univ Vienna, Vienna, Austria
[5] Hietzing Hosp, Vienna, Austria
[6] Abbott, Rungis, France
[7] Abbott GmbH & Co KG, Ludwigshafen, Germany
[8] Abbott, Abbott Pk, IL USA
[9] Univ Calif San Diego, San Diego, CA 92103 USA
来源
ARTHRITIS AND RHEUMATISM | 2011年 / 63卷 / 10期
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1231
引用
收藏
页码:S481 / S481
页数:1
相关论文
共 50 条
  • [21] Long-Term Safety and Efficacy of Certolizumab Pegol in Combination with Methotrexate in the Treatment of Rheumatoid Arthritis: 5-Year Results from a 24-Week Randomized Controlled Trial and Open-Label Extension Study
    Smolen, Josef
    Van Vollenhoven, Ronald
    Kavanaugh, Arthur
    Strand, Vibeke
    Vencovsky, Jiri
    Schiff, Michael
    Landewe, Robert
    Haraoui, Boulos
    Walker, Susan
    van der Heijde, Desiree
    JOURNAL OF RHEUMATOLOGY, 2014, 41 (07) : 1506 - 1507
  • [22] LONG-TERM BENEFITS OF 4-WEEKLY CERTOLIZUMAB PEGOL MONOTHERAPY AND COMBINATION THERAPY ON HOUSEHOLD PRODUCTIVITY AND SOCIAL PARTICIPATION IN RHEUMATOID ARTHRITIS: 5-YEAR RESULTS FROM AN OPEN-LABEL EXTENSION STUDY
    Strand, V.
    Purcaru, O.
    van Vollenhoven, R.
    Choy, E.
    Fleischmann, R.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 72 : 441 - 442
  • [23] Long-Term Safety and Efficacy Of Certolizumab Pegol In Combination With Methotrexate In The Treatment Of Rheumatoid Arthritis: 5-Year Results From a 24-Week Randomized Controlled Trial and Open-Label Extension Study
    Smolen, Josef S.
    van Vollenhoven, Ronald
    Kavanaugh, Arthur
    Strand, Vibeke
    Vencovsky, Jiri
    Schiff, Michael H.
    Landewe, Robert
    Haraoui, Boulos
    Walker, Susan
    van der Heijde, Desiree
    ARTHRITIS AND RHEUMATISM, 2013, 65 : S988 - S989
  • [24] Long-Term Safety and Efficacy Of Certolizumab Pegol In Combination With Methotrexate In The Treatment Of Rheumatoid Arthritis: 5-Year Results From a 52-Week Randomized Controlled Trial and Open-Label Extension Study
    Keystone, Edward
    Landewe, Robert
    van Vollenhoven, Ronald
    Combe, Bernard
    Strand, Vibeke
    Mease, Philip J.
    Shaughnessy, Laura
    VanLunen, Brenda
    van der Heijde, Desiree
    ARTHRITIS AND RHEUMATISM, 2013, 65 : S596 - S597
  • [25] Patient-Reported Outcomes of Long-Term Upadacitinib Use in Patients with Rheumatoid Arthritis: Interim Analysis Results of a Phase 2, Open-Label Extension Study
    Strand, Vibeke
    Tundia, Namita
    Friedman, Alan
    ARTHRITIS & RHEUMATOLOGY, 2017, 69
  • [26] Long-Term Safety and Efficacy of 4-Weekly Certolizumab Pegol Combination and Monotherapy in Rheumatoid Arthritis: 5 Year Results from an Open Label Extension Study
    Fleischmann, Roy M.
    van Vollenhoven, Ronald F.
    Vencovsky, Jiri
    Alten, Rieke
    Davies, Owen
    Stach, Christian
    de Longueville, Marc
    Van Lunen, Brenda
    Choy, Ernest
    ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : S565 - S566
  • [27] Long-term adalimumab efficacy in patients with moderate-to-severe hidradenitis suppurativa/acne inversa: 3-year results of a phase 3 open-label extension study
    Zouboulis, Christos C.
    Okun, Martin M.
    Prens, Errol P.
    Gniadecki, Robert
    Foley, Peter A.
    Lynde, Charles
    Weisman, Jamie
    Gu, Yihua
    Williams, David A.
    Jemec, Gregor B. E.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2019, 80 (01) : 60 - +
  • [28] Long-Term Efficacy of Lacosamide as Adjunctive Therapy in Patients with Uncontrolled POS: Results from a Phase III Open-Label Extension Trial
    Chung, Steve
    Faught, Raymond Edward
    Husain, Aatif
    Isojarvi, Jouko
    Doty, Pamela
    NEUROLOGY, 2011, 76 (09) : A376 - A376
  • [29] LONG-TERM SAFETY AND EFFICACY OF LACOSAMIDE AS ADJUNCTIVE THERAPY IN PATIENTS WITH UNCONTROLLED POS: RESULTS FROM A PHASE III OPEN-LABEL EXTENSION TRIAL
    Husain, A.
    Faught, E.
    Chung, S.
    Isojarvi, J.
    McShea, C.
    Doty, P.
    EPILEPSIA, 2011, 52 : 155 - 155
  • [30] Certolizumab pegol plus methotrexate 5-year results from the rheumatoid arthritis prevention of structural damage (RAPID) 2 randomized controlled trial and long-term extension in rheumatoid arthritis patients
    Josef S. Smolen
    Ronald van Vollenhoven
    Arthur Kavanaugh
    Vibeke Strand
    Jiri Vencovsky
    Michael Schiff
    Robert Landewé
    Boulos Haraoui
    Catherine Arendt
    Irina Mountian
    David Carter
    Désirée van der Heijde
    Arthritis Research & Therapy, 17