Evaluation of service mammography screening impact in Italy. The contribution of hazard analysis

被引:12
作者
Paci, Eugenio [1 ]
Coviello, Enzo [2 ]
Miccinesi, Guido [1 ]
Puliti, Donella [1 ]
Cortesi, Laura [3 ]
De Lisi, Vincenzo [4 ]
Ferretti, Stefano [5 ]
Mangone, Lucia [6 ]
Perlangeli, Vincenza [7 ]
Ponti, Antonio [8 ]
Ravaioli, Alessandra [9 ]
de Biancho, Priscilla Sassoli [10 ]
Segnan, Nereo [8 ]
Stracci, Fabrizio [11 ]
Tumino, Rosario [12 ]
Zarcone, Maurizio [13 ]
Zorzi, Manuel [14 ]
Zappa, Marco [1 ]
机构
[1] CSPO Res Inst Tuscany Reg, Clin & Descript Epidemiol Unit, I-50135 Florence, Italy
[2] Epidemiol Unit ASL BA 2, I-70054 Bari, Italy
[3] Modena Canc Registry, I-41100 Modena, Italy
[4] Parma Canc Registry, I-43100 Parma, Italy
[5] Ferrara Canc Registry, I-44100 Ferrara, Italy
[6] Reggio Emilia Canc Registry, I-42100 Reggio Emilia, Italy
[7] AUSL Bologna, I-40068 Bologna, Italy
[8] Epidemiol Unit CPO Piemonte, I-10123 Turin, Italy
[9] Romagna Canc Registry, I-47100 Forli, Italy
[10] Emilia Romagna Reg Hlth Dept, I-40127 Bologna, Italy
[11] Umbria Canc Registry, I-06100 Perugia, Italy
[12] AO Civile MP Arezzo, Canc Registry, I-97100 Ragusa, Italy
[13] Palermo Breast Canc Registry, I-90127 Palermo, Italy
[14] Ist Oncol Veneto, Venetian Tumour Registry, I-35128 Padua, Italy
关键词
breast cancer; service screening; survival;
D O I
10.1016/j.ejca.2008.02.026
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
12,987 invasive breast cancer cases were diagnosed in women aged 50-69 upto the year 2001 in nine Italian areas where a screening programme was active. Cases were followed up in 2005 for a total of 1921 breast cancer failures. The 10-year survival rates were 85.3% for the invited group against 75.6% for the non-invited. A time dependent analysis was performed using S-year intervals. Crude hazard ratios for the invited group in comparison to the not invited group were 0.52 and 0.64 respectively in the (0-5) year and [5-10] year time windows. Hazard ratio adjusted for tumour characteristics was 0.96 in the [5-10] year time window, suggesting minimal or any length bias. Consistent with the results of randomised trials, these analyses of service screening data document a mortality reduction of 36% at 5-10 years after diagnosis. (c) 2008 Elsevier Ltd. All rights reserved
引用
收藏
页码:858 / 865
页数:8
相关论文
共 37 条
[1]  
AIRT Working Group, 2006, Epidemiol Prev, V30, P8
[2]  
AIRTUM Working group, 2007, EPIDEMIOL PREV S1, V30, P14
[3]   MAMMOGRAPHIC SCREENING AND MORTALITY FROM BREAST-CANCER - THE MALMO MAMMOGRAPHIC SCREENING TRIAL [J].
ANDERSSON, I ;
ASPERGREN, K ;
JANZON, L ;
LANDBERG, T ;
LINDHOLM, K ;
LINELL, F ;
LJUNGBERG, O ;
RANSTAM, J ;
SIGFUSSON, B .
BRITISH MEDICAL JOURNAL, 1988, 297 (6654) :943-948
[4]  
Baker S. G., 2004, BMC MED RES METHODOL, V4, P1
[5]   Effects of study methods and biases on estimates of invasive breast cancer overdetection with mammography screening: a systematic review [J].
Biesheuvel, Corne ;
Barratt, Alexandra ;
Howard, Kirsten ;
Houssami, Nehmat ;
Irwig, Les .
LANCET ONCOLOGY, 2007, 8 (12) :1129-1138
[6]   Breast cancer screening - time to move forward [J].
Cuzick, J .
BREAST, 2002, 11 (03) :209-210
[7]   Overdiagnosis and breast cancer screening [J].
Day, NE .
BREAST CANCER RESEARCH, 2005, 7 (05) :228-229
[8]   Reduction in breast cancer mortality from organized service screening with mammography:: 1.: Further confirmation with extended data [J].
Duffy, SW ;
Tabár, L ;
Chen, THH ;
Smith, RA ;
Holmberg, L ;
Jonsson, H ;
Lenner, P ;
Nyström, L ;
Törnberg, S .
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2006, 15 (01) :45-51
[9]  
DUFFY SW, 2001, QUANTITATIVE METHODS
[10]   Screening for breast cancer [J].
Elmore, JG ;
Armstrong, K ;
Lehman, CD ;
Fletcher, SW .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 293 (10) :1245-1256