Detection of Kawasaki disease-associated antigen in inflamed gastrointestinal tract in acute Kawasaki disease

被引：7

作者：

Miura, M ^{[1
]}

Garcia, FL

Crawford, SE

Rowley, AH

机构：

[1] Northwestern Univ, Dept Pediat, Chicago, IL 60611 USA

[2] Northwestern Univ, Dept Pathol, Chicago, IL 60611 USA

[3] Childrens Mem Hosp, Chicago, IL 60614 USA

[4] Feinberg Sch Med, Chicago, IL USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2005年 / 24卷 / 10期

关键词：

gastrointestinal tract; immunohistochemistry; Kawasaki disease; kidney; synthetic antibody;

D O I：

10.1097/01.inf.0000180973.98862.50

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We performed immunohistochemistry experiments using synthetic antibodies on the gastrointestinal tract and kidney from acute Kawasaki disease patients. Significant gastrointestinal tract inflammation was present in only 2/7 patients, who had antigen detected at the site of inflammation. Antigen was not detected in kidney from 6 patients. The presence of antigen may be related to gastrointestinal pathology in acute Kawasaki disease.

引用

页码：927 / 929

页数：3

共 10 条

[1]

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[2] Pathogenesis of poliovirus infection in PVRTg mice: poliovirus replicates in peritoneal macrophages [J].