Noninvasive Assessment of Liver Parenchyma Using Gray-Scale Ultrasound-Based Histogram Analysis in Patients With Chronic Hepatitis B Infection

被引:6
作者
Beyazal, Mehmet [1 ]
Polat, Hatice Beyazal [2 ]
Erturk, Ayse [3 ]
Bedir, Recep [4 ]
机构
[1] Recep Tayyip Erdogan Univ, Sch Med, Dept Radiol, Rize, Turkey
[2] Recep Tayyip Erdogan Univ, Sch Med, Dept Internal Med, Rize, Turkey
[3] Recep Tayyip Erdogan Univ, Sch Med, Dept Infect Dis, Rize, Turkey
[4] Recep Tayyip Erdogan Univ, Sch Med, Dept Pathol, Rize, Turkey
关键词
chronic hepatitis B; hepatic fibrosis; gray-scale ultrasound images; histogram analysis; APPARENT DIFFUSION-COEFFICIENT; LEVEL HISTOGRAM; CERVICAL-CANCER; WEIGHTED MRI; FIBROSIS; UTILITY; MAPS;
D O I
10.1097/RUQ.0000000000000438
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The aims of this study were to examine the alterations of liver echo-intensity histogram parameters in chronic hepatitis B (CHB) patients and to assess the potential role of histogram parameters in the evaluation of hepatic fibrosis. A total of 52 patients with CHB who underwent liver biopsies were included in the study. The control group consisted of 30 healthy individuals. Histogram parameters were obtained from histogram analysis of gray-scale ultrasound images of both groups. The histogram parameters of the groups were compared. The association of histogram parameters with the grading and staging of histological activity index (HAI) in patients with CHB were evaluated. The patient group had statistically significant lower skewness, kurtosis, and higher variance, mean, 50th, and 90th percentile values compared with control group. When patients with CHB were divided into subgroups according to HAI stage, there was the increasing trend in skewness values and decreasing trend in kurtosis values across subgroups. The first percentile values showed negative correlation with HAI staging in patients with CHB. Ultrasound is a fast, inexpensive, and reproducible imaging method; histogram analysis of gray-scale ultrasound images may provide useful information for evaluation of hepatic fibrosis in CHB patients.
引用
收藏
页码:69 / 73
页数:5
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