Relevance of New Conduction Disorders After Implantation of the ACURATE Neo Transcatheter Heart Valve in the Aortic Valve Position

被引:8
作者
Brinkert, Miriam [1 ]
Wolfrum, Mathias [1 ]
Moccetti, Federico [1 ]
Bossard, Matthias [1 ]
Berte, Benjamin [1 ]
Cuculi, Florim [1 ]
Kobza, Richard [1 ]
Toggweiler, Stefan [1 ]
机构
[1] Luzerner Kantonsspital, Heart Ctr Lucerne, Div Cardiol, Luzern, Switzerland
关键词
PERMANENT PACEMAKER IMPLANTATION; CLINICAL-OUTCOMES; REPLACEMENT; DEVICES; IMPACT; BLOCK; RISK;
D O I
10.1016/j.amjcard.2019.11.036
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The ACURATE neo transcatheter heart valve has been associated with very low rates of new conduction disorders (CDs). We assessed the clinical relevance of new CDs in patients undergoing transcatheter aortic valve replacement (TAVR) with this valve. Data of consecutive patients without a pre-existing left bundle branch block (LBBB) or a permanent pacemaker (PPM) undergoing TAVR with the ACURATE neo were analyzed from the prospective SwissTAVI registry. Patients with new CDs were compared with patients with an unchanged electrocardiogram (ECG). ACURATE neo was implanted in 203 patients (mean age 82 +/- 6 years, 63% women), CDs occurred in 28 patients (22 [11 %] developed a LBBB, 6 [3%] required a PPM). New CDs resulted in a longer median duration of hospitalization (7 vs 5 days, interquartile range 4 to 13 vs 3 to 8 days, p = 0.04). At 1-year follow-up, left ventricular ejection fraction was significantly lower in patients with new CDs compared with patients with an unchanged ECG (54% +/- 13% vs 61% +/- 9%, p < 0.01). Kaplan-Meier estimates of survival at 1-year were 89% in patients with new CDs and 95% in patients with an unchanged ECG (hazard ratio 2.0, 95% confidence interval 0.7 to 6.2, p = 0.22). After TAVR with the self-expanding ACURATE neo valve, the rate of new CDs, including complete LBBB was low and very few patients required a new PPM. However, new CDs prolonged initial hospitalization and increased the risk for left ventriculardysfunction at 1-year follow-up. Patients without new CDs had excellent outcomes with a very high survival rate at 1-year follow-up. (C) 2019 Elsevier Inc. All rights reserved.
引用
收藏
页码:783 / 787
页数:5
相关论文
共 17 条
  • [1] Comparison of Transfemoral Transcatheter Aortic Valve Replacement Performed in the Catheterization Laboratory (Minimalist Approach) Versus Hybrid Operating Room (Standard Approach) Outcomes and Cost Analysis
    Babaliaros, Vasilis
    Devireddy, Chandan
    Lerakis, Stamatios
    Leonardi, Robert
    Iturra, Sebastian A.
    Mavromatis, Kreton
    Leshnower, Bradley G.
    Guyton, Robert A.
    Kanitkar, Mihir
    Keegan, Patricia
    Simone, Amy
    Stewart, James P.
    Ghasemzadeh, Nima
    Block, Peter
    Thourani, Vinod H.
    [J]. JACC-CARDIOVASCULAR INTERVENTIONS, 2014, 7 (08) : 898 - 904
  • [2] Changes in the Pacemaker Rate After Transition From Edwards SAPIEN XT to SAPIEN 3 Transcatheter Aortic Valve Implantation The Critical Role of Valve Implantation Height
    De Torres-Alba, Fernando
    Kaleschke, Gerrit
    Diller, Gerhard Paul
    Vormbrock, Julia
    Orwat, Stefan
    Radke, Robert
    Reinke, Florian
    Fischer, Dieter
    Reinecke, Holger
    Baumgartner, Helmut
    [J]. JACC-CARDIOVASCULAR INTERVENTIONS, 2016, 9 (08) : 805 - 813
  • [3] Correlation of Device Landing Zone Calcification and Acute Procedural Success in Patients Undergoing Transcatheter Aortic Valve Implantations With the Self-Expanding CoreValve Prosthesis
    John, Daniel
    Buellesfeld, Lutz
    Yuecel, Seyrani
    Mueller, Ralf
    Latsios, Georg
    Beucher, Harald
    Gerckens, Ulrich
    Grube, Eberhard
    [J]. JACC-CARDIOVASCULAR INTERVENTIONS, 2010, 3 (02) : 233 - 243
  • [4] Mortality and Heart Failure Hospitalization in Patients With Conduction Abnormalities After Transcatheter Aortic Valve Replacement
    Jorgensen, Troels H.
    De Backer, Ole
    Gerds, Thomas A.
    Bieliauskas, Gintautas
    Svendsen, Jesper H.
    Sondergaard, Lars
    [J]. JACC-CARDIOVASCULAR INTERVENTIONS, 2019, 12 (01) : 52 - 61
  • [5] The SAVI-TF Registry 1-Year Outcomes of the European Post-Market Registry Using the ACURATE neo Transcatheter Heart Valve Under Real-World Conditions in 1,000 Patients
    Kim, Won-Keun
    Hengstenberg, Christian
    Hilker, Michael
    Kerber, Sebastian
    Schaefer, Ulrich
    Rudolph, Tanja
    Linke, Axel
    Franz, Norbert
    Kuntze, Thomas
    Nef, Holger
    Kappert, Utz
    Zembala, Michael O.
    Toggweiler, Stefan
    Walther, Thomas
    Moellmann, Helge
    [J]. JACC-CARDIOVASCULAR INTERVENTIONS, 2018, 11 (14) : 1368 - 1374
  • [6] Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients
    Mack, M. J.
    Leon, M. B.
    Thourani, V. H.
    Makkar, R.
    Kodali, S. K.
    Russo, M.
    Kapadia, S. R.
    Malaisrie, S. C.
    Cohen, D. J.
    Pibarot, P.
    Leipsic, J.
    Hahn, R. T.
    Blanke, P.
    Williams, M. R.
    McCabe, J. M.
    Brown, D. L.
    Babaliaros, V.
    Goldman, S.
    Szeto, W. Y.
    Genereux, P.
    Pershad, A.
    Pocock, S. J.
    Alu, M. C.
    Webb, J. G.
    Smith, C. R.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2019, 380 (18) : 1695 - 1705
  • [7] Transfemoral aortic valve replacement with the repositionable Lotus Valve System in high surgical risk patients: the REPRISE I study
    Meredith, Ian T.
    Worthley, Stephen G.
    Whitbourn, Robert J.
    Antonis, Paul
    Montarello, Joseph K.
    Newcomb, Andrew E.
    Lockwood, Siohban
    Haratani, Nicole
    Allocco, Dominic J.
    Dawkins, Keith D.
    [J]. EUROINTERVENTION, 2014, 9 (11) : 1264 - 1270
  • [8] Outcomes following pacemaker implantation after transcatheter aortic valve implantation with CoreValve® devices: Results from the FRANCE 2 Registry
    Mouillet, Gauthier
    Lellouche, Nicolas
    Yamamoto, Masanori
    Oguri, Atsushi
    Dubois-Rande, Jean-Luc
    Van Belle, Eric
    Gilard, Martine
    Laskar, Marc
    Teiger, Emmanuel
    [J]. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2015, 86 (03) : E158 - E166
  • [9] Predictors and Clinical Outcomes of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement The PARTNER (Placement of AoRtic TraNscathetER Valves) Trial and Registry
    Nazif, Tamim M.
    Dizon, Jose M.
    Hahn, Rebecca T.
    Xu, Ke
    Babaliaros, Vasilis
    Douglas, Pamela S.
    El-Chami, Mikhael F.
    Herrmann, Howard C.
    Mack, Michael
    Makkar, Raj R.
    Miller, Craig
    Pichard, Augusto
    Tuzcu, E. Murat
    Szeto, Wilson Y.
    Webb, John G.
    Moses, Jeffrey W.
    Smith, Craig R.
    Williams, Mathew R.
    Leon, Martin B.
    Kodali, Susheel K.
    [J]. JACC-CARDIOVASCULAR INTERVENTIONS, 2015, 8 (01) : 60 - 69
  • [10] A Pathway to Earlier Discharge Following TAVI: Assessment of Safety and Resource Utilization
    Noad, Rebecca L.
    Johnston, Nicola
    McKinley, Andrew
    Dougherty, Mark
    Nzewi, O. C.
    Jeganathan, Reuben
    Manoharan, Ganesh
    Spence, Mark S.
    [J]. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2016, 87 (01) : 134 - 142