Biomimetic synthesis of needle-like fluorescent calcium phosphate/carbon dot hybrid composites for cell labeling and copper ion detection

被引：15

作者：

Guo, Shanshan ^{[1
]}

Lu, Shousi ^{[1
,2
]}

Xu, Pingxiang ^{[1
,3
]}

Ma, Yi ^{[1
]}

Zhao, Liang ^{[1
]}

Zhao, Yuming ^{[1
,3
]}

Gu, Wei ^{[4
]}

Xue, Ming ^{[1
,3
]}

机构：

[1] Capital Med Univ, Sch Basic Med Sci, Dept Pharmacol, Beijing 100069, Peoples R China

[2] China Rehabil Res Ctr, Beijing 100069, Peoples R China

[3] Beijing Lab Biomed Detect Technol & Instrument, Beijing 100069, Peoples R China

[4] Capital Med Univ, Sch Chem Biol & Pharmaceut Sci, Dept Chem Biol, Beijing 100069, Peoples R China

来源：

DALTON TRANSACTIONS | 2016年 / 45卷 / 18期

基金：

北京市自然科学基金;

关键词：

CARBON QUANTUM DOTS; ASSISTED POLYOL SYNTHESIS; POLYMER NANODOTS; GENE DELIVERY; HYDROXYAPATITE; NANOPARTICLES; RECOGNITION; NITRIDE; PROBES; ZINC;

D O I：

10.1039/c6dt00395h

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Herein, we report a biomimetic method to synthesize needle-like calcium phosphate (CaP) with dimensions of similar to 130 nm length and similar to 30 nm width using carbon dots (CDs) and sodium carboxymethylcellulose as dual templates. In addition to acting as the template, the CDs enable the CaP/CDs hybrid composites to emit blue fluorescence under UV excitation. Moreover, the prepared CaP/CDs exhibited a negligible cytotoxicity towards HeLa cells. The potential of these CaP/CDs as a fluorescent probe for cell labeling was tested. In addition, it was demonstrated that the CaP/CDs were capable of selective detection of copper ions in drinking water.

引用

页码：7665 / 7671

页数：7

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