The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder

被引：757

作者：

Faraone, Stephen, V ^{[1
,2
,3
,4
]}

Banaschewski, Tobias ^{[5
,6
,7
]}

Coghill, David ^{[8
,9
]}

Zheng, Yi ^{[10
,11
,12
,13
,14
,15
]}

Biederman, Joseph ^{[16
,17
]}

Bellgrove, Mark A. ^{[18
,19
,20
]}

Newcorn, Jeffrey H. ^{[4
,21
,22
]}

Gignac, Martin ^{[23
,24
,25
]}

Al Saud, Nouf M. ^{[26
]}

Manor, Iris ^{[27
,28
]}

Rohde, Luis Augusto ^{[29
]}

Yang, Li ^{[30
,31
]}

Cortese, Samuele ^{[32
,33
,34
,35
,36
,37
]}

Almagor, Doron ^{[25
,38
]}

Stein, Mark A. ^{[39
,40
]}

Albatti, Turki H. ^{[41
]}

Aljoudi, Haya F. ^{[41
,42
]}

Alqahtani, Mohammed M. J. ^{[26
,43
]}

Asherson, Philip ^{[44
]}

Atwoli, Lukoye ^{[45
,46
,47
,48
,49
]}

Bolte, Sven ^{[50
,51
,52
,53
]}

Buitelaar, Jan K. ^{[54
]}

Crunelle, Cleo L. ^{[55
,56
]}

Daley, David ^{[36
,57
,58
]}

Dalsgaard, Soren ^{[59
,60
]}

Doepfner, Manfred ^{[61
,62
,63
]}

Espinet, Stacey ^{[64
]}

Fitzgerald, Michael ^{[65
]}

Franke, Barbara ^{[66
,67
,68
,164
]}

Gerlach, Manfred ^{[66
,164
]}

Haavik, Jan ^{[69
,70
]}

Hartman, Catharina A. ^{[71
,72
,73
,74
]}

Hartung, Cynthia M. ^{[75
]}

Hinshaw, Stephen P. ^{[76
,77
]}

Hoekstra, Pieter J. ^{[78
]}

Hollis, Chris ^{[35
,36
,79
,80
,81
]}

Kollins, Scott H. ^{[82
,83
]}

Kooij, J. J. Sandra ^{[84
,85
,86
,87
,129
]}

Kuntsi, Jonna ^{[88
]}

Larsson, Henrik ^{[89
,90
]}

Li, Tingyu ^{[91
,92
,93
]}

Liu, Jing ^{[14
,15
,30
,31
,94
]}

Merzon, Eugene ^{[95
,96
,97
,98
]}

Mattingly, Gregory ^{[99
,163
]}

Mattos, Paulo ^{[100
,101
,102
]}

McCarthy, Suzanne ^{[103
]}

Mikami, Amori Yee ^{[104
]}

Molina, Brooke S. G. ^{[105
,106
,107
,108
]}

Nigg, Joel T. ^{[109
]}

Purper-Ouakil, Diane ^{[110
,111
]}

机构：

[1] SUNY Upstate Med Univ, Psychiat Res Div, Dept Psychiat, Syracuse, NY 13210 USA

[2] SUNY Upstate Med Univ, Dept Neurosci, Psychiat Res Div, Syracuse, NY 13210 USA

[3] World Federat ADHD, Zurich, Switzerland

[4] Amer Profess Soc ADHD & Related Disorders APSARD, Brentwood, TN USA

[5] Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Dept Child & Adolescent Psychiat & Psychotherapy, Mannheim, Germany

[6] Zent ADHS Netz, Child & Adolescent Psychiatrists Representat, Cologne, Germany

[7] German Assoc Child & Adolescent Psychiat & Psycho, Cologne, Germany

[8] Univ Melbourne, Fac Med Dent & Hlth Sci, Dept Paediat, Melbourne, Vic, Australia

[9] Univ Melbourne, Fac Med Dent & Hlth Sci, Dept Psychiat, Melbourne, Vic, Australia

[10] Capital Med Univ, Beijing Anding Hosp, Beijing, Peoples R China

[11] Natl Clin Res Ctr Mental Disorders, Beijing, Peoples R China

[12] Beijing Key Lab Mental Disorders, Beijing, Peoples R China

[13] Beijing Inst Brain Disorders, Beijing, Peoples R China

[14] Asian Federat ADHD, Beijing, Peoples R China

[15] Chinese Soc Child & Adolescent Psychiat, Beijing, Peoples R China

[16] Massachusetts Gen Hosp, Clin & Res Programs Pediat Psychopharmacol & Adul, Boston, MA 02114 USA

[17] Harvard Med Sch, Dept Psychiat, Boston, MA 02115 USA

[18] Monash Univ, Turner Inst Brain & Mental Hlth, Clayton, Vic, Australia

[19] Monash Univ, Sch Psychol Sci, Clayton, Vic, Australia

[20] Australian ADHD Professionals Assoc AADPA, Melbourne, Vic, Australia

[21] Icahn Sch Med Mt Sinai, Dept Psychiat, Div ADHD & Learning Disorders, New York, NY 10029 USA

[22] Icahn Sch Med Mt Sinai, Div ADHD & Learning Disorders, Dept Pediat, New York, NY 10029 USA

[23] MUHC, Dept Child & Adolescent Psychiat, Montreal Childrens Hosp, Montreal, PQ, Canada

[24] McGill Univ, Child & Adolescent Psychiat Div, Montreal, PQ, Canada

[25] Canadian ADHD Res Alliance CADDRA, Toronto, ON, Canada

[26] Saudi ADHD Soc, Riyadh, Saudi Arabia

[27] Israeli Soc ADHD ISA, Tel Aviv, Israel

[28] EPA European Psychiat Assoc, Neurodev Sect, Strasbourg, France

[29] Univ Fed Rio Grande do Sul, Dept Psychiat, Belo Horizonte, MG, Brazil

[30] Peking Univ Sixth Hosp, Natl Clin Res Ctr Mental Disorders, Inst Mental Hlth, Beijing, Peoples R China

[31] Peking Univ, NHC Key Lab Mental Hlth, Beijing, Peoples R China

[32] Univ Southampton, Fac Environm & Life Sci, Ctr Innovat Mental Hlth, Sch Psychol, Southampton, Hants, England

[33] Univ Southampton, Fac Med, Clin & Expt Sci CNS & Psychiat, Southampton, Hants, England

[34] Solent NHS Trust, Southampton, Hants, England

[35] NYU, NYU Langone, Child Study Ctr, Hassenfeld Childrens Hosp, New York, NY USA

[36] Univ Nottingham, Sch Med, Div Psychiat & Appl Psychol, Nottingham, England

[37] Univ Nottingham, Nottingham, England

[38] Univ Toronto, SickKids Ctr Community Mental Hlth, Toronto, ON, Canada

[39] Univ Washington, Seattle, WA 98195 USA

[40] Seattle Childrens Hosp, Seattle, WA USA

[41] Saudi ADHD Soc Med & Psychol Comm, Riyadh, Saudi Arabia

[42] King Faisal Specialist Hosp & Res Ctr, Riyadh, Saudi Arabia

[43] King Khalid Univ, Clin Psychol, Abha, Saudi Arabia

[44] Kings Coll London, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat, London, England

[45] Moi Univ, Dept Mental Hlth & Behav Sci, Sch Med, Eldoret, Kenya

[46] Aga Khan Univ, Med Coll East Africa, Brain & Mind Inst, Nairobi, Kenya

[47] Aga Khan Univ, Med Coll East Africa, Dept Internal Med, Nairobi, Kenya

[48] African Coll Psychopharmacol, Nairobi, Kenya

[49] African Assoc Psychiatrists, Nairobi, Kenya

[50] Karolinska Inst, Ctr Neurodev Disorders KIND, Ctr Psychiat Res, Dept Womens & Childrens Hlth, Region Stockholm, Sweden

来源：

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS | 2021年 / 128卷

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

ADHD; Diagnosis; Treatment; Course; Outcome; Genetics; Brain; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT-HYPERACTIVITY DISORDER; ABNORMAL-PSYCHICAL-CONDITIONS; POLYUNSATURATED FATTY-ACIDS; META-REGRESSION ANALYSIS; TRAUMATIC BRAIN-INJURY; OF-THE-LITERATURE; FOLLOW-UP; MATERNAL SMOKING; YOUNG-ADULTS;

D O I：

10.1016/j.neubiorev.2021.01.022

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Background: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and pre-vent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. Methods: We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For network meta-analyses we required comparison adjusted funnel plots. We excluded treatment studies with waiting-list or treatment as usual controls. From this literature, we extracted evidence-based assertions about the disorder. Results: We generated 208 empirically supported statements about ADHD. The status of the included statements as empirically supported is approved by 80 authors from 27 countries and 6 continents. The contents of the manuscript are endorsed by 366 people who have read this document and agree with its contents. Conclusions: Many findings in ADHD are supported by meta-analysis. These allow for firm statements about the nature, course, outcome causes, and treatments for disorders that are useful for reducing misconceptions and stigma.

引用

页码：789 / 818

页数：30

共 279 条

[1] Mild Traumatic Brain Injury and ADHD: A Systematic Review of the Literature and Meta-Analysis [J].

Adeyemo, Bamidele O. ;

Biederman, Joseph ;

Zafonte, Ross ;

Kagan, Elana ;

Spencer, Thomas J. ;

Uchida, Mai ;

Kenworthy, Tara ;

Spencer, Andrea E. ;

Faraone, Stephen V. .

JOURNAL OF ATTENTION DISORDERS, 2014, 18 (07) :576-584

[2] Psychiatric and Nonpsychiatric Comorbidities Among Children With ADHD: An Exploratory Analysis of Nationwide Claims Data in Germany [J].

Akmatov, Manas K. ;

Ermakova, Tatiana ;

Baetzing, Joerg .

JOURNAL OF ATTENTION DISORDERS, 2021, 25 (06) :874-884

[3]

Alliance, 2011, CANADIAN ADHD PRACTI

[4] Maternal body mass index before pregnancy as a risk factor for ADHD and autism in children [J].

Andersen, Christina Hebsgaard ;

Thomsen, Per Hove ;

Nohr, Ellen Aagaard ;

Lemcke, Sanne .

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2018, 27 (02) :139-148

[5] Analysis of shared heritability in common disorders of the brain [J].

Anttila, Verneri ;

Bulik-Sullivan, Brendan ;

Finucane, Hilary K. ;

Walters, Raymond K. ;

Bras, Jose ;

Duncan, Laramie ;

Escott-Price, Valentina ;

Falcone, Guido J. ;

Gormley, Padhraig ;

Malik, Rainer ;

Patsopoulos, Nikolaos A. ;

Ripke, Stephan ;

Wei, Zhi ;

Yu, Dongmei ;

Lee, Phil H. ;

Turley, Patrick ;

Grenier-Boley, Benjamin ;

Chouraki, Vincent ;

Kamatani, Yoichiro ;

Berr, Claudine ;

Letenneur, Luc ;

Hannequin, Didier ;

Amouyel, Philippe ;

Boland, Anne ;

Deleuze, Jean-Francois ;

Duron, Emmanuelle ;

Vardarajan, Badri N. ;

Reitz, Christiane ;

Goate, Alison M. ;

Huentelman, Matthew J. ;

Kamboh, M. Ilyas ;

Larson, Eric B. ;

Rogaeva, Ekaterina ;

St George-Hyslop, Peter ;

Hakonarson, Hakon ;

Kukull, Walter A. ;

Farrer, Lindsay A. ;

Barnes, Lisa L. ;

Beach, Thomas G. ;

Demirci, F. Yesim ;

Head, Elizabeth ;

Hulette, Christine M. ;

Jicha, Gregory A. ;

Kauwe, John S. K. ;

Kaye, Jeffrey A. ;

Leverenz, James B. ;

Levey, Allan I. ;

Lieberman, Andrew P. ;

Pankratz, Vernon S. ;

Poon, Wayne W. .

SCIENCE, 2018, 360 (6395) :1313-+

[6]

APA, 2013, Diagnostic and Statistical Manual of Mental Disorders: DSM-V, V5th

[7] A Decade of EEG Theta/Beta Ratio Research in ADHD: A Meta-Analysis [J].

Arns, Martijn ;

Conners, C. Keith ;

Kraemer, Helena C. .

JOURNAL OF ATTENTION DISORDERS, 2013, 17 (05) :374-383

[8] ADHD Is Comorbid to Migraine in Childhood: A Population-Based Study [J].

Arruda, Marco Antonio ;

Arruda, Renato ;

Guidetti, Vincenzo ;

Bigal, Marcelo Eduardo .

JOURNAL OF ATTENTION DISORDERS, 2020, 24 (07) :990-1001

[9]

Australian ADHD Professionals Association, 2019, SOC EC COSTS ADHD AU

[10]

Barkley RA, 2002, CLIN CHILD FAM PSYCH, V5, P89

← 1 2 3 4 5 6 7 8 9 10 →