AMBER LENSES TO BLOCK BLUE LIGHT AND IMPROVE SLEEP: A RANDOMIZED TRIAL

被引:86
作者
Burkhart, Kimberly [2 ]
Phelps, James R. [1 ]
机构
[1] Samaritan Mental Hlth, Corvallis, OR 97330 USA
[2] Univ Toledo, Toledo, OH USA
关键词
Insomnia; Sleep quality; Amber lenses; Blue light; Dark therapy; CYCLING BIPOLAR PATIENT; MELATONIN SUPPRESSION; ACTION SPECTRUM; DARK THERAPY; MELANOPSIN; VALIDATION; DISORDER; DURATION; GLASSES; HUMANS;
D O I
10.3109/07420520903523719
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
All light is not equal: blue wavelengths are the most potent portion of the visible electro-magnetic spectrum for circadian regulation. Therefore, blocking blue light could create a form of physiologic darkness. Because the timing and quantity of light and darkness both affect sleep, evening use of amber lenses to block blue light might affect sleep quality. Mood is also affected by light and sleep; therefore, mood might be affected by blue light blockade. In this study, 20 adult volunteers were randomized to wear either blue-blocking (amber) or yellow-tinted (blocking ultraviolet only) safety glasses for 3 h prior to sleep. Participants completed sleep diaries during a one-week baseline assessment and two weeks' use of glasses. Outcome measures were subjective: change in overall sleep quality and positive/negative affect. Results demonstrated that sleep quality at study outset was poorer in the amber lens than the control group. Two- by three-way ANOVA revealed significant (p < .001) interaction between quality of sleep over the three weeks and experimental condition. At the end of the study, the amber lens group experienced significant (p < .001) improvement in sleep quality relative to the control group and positive affect (p = .005). Mood also improved significantly relative to controls. A replication with more detailed data on the subjects' circadian baseline and objective outcome measures is warranted. (Author correspondence: jphelps@samhealth.org)
引用
收藏
页码:1602 / 1612
页数:11
相关论文
共 34 条
[1]   Dark therapy for mania: a pilot study [J].
Barbini, B ;
Benedetti, F ;
Colombo, C ;
Dotoli, D ;
Bernasconi, A ;
Cigala-Fulgosi, M ;
Florita, M ;
Smeraldi, E .
BIPOLAR DISORDERS, 2005, 7 (01) :98-101
[2]   Light exposure, melatonin secretion, and menstrual cycle parameters: An integrative review [J].
Barron, Mary Lee .
BIOLOGICAL RESEARCH FOR NURSING, 2007, 9 (01) :49-69
[3]   Changes in self-reported sleep duration predict mood changes in bipolar disorder [J].
Bauer, Michael ;
Glenn, Tasha ;
Whybrow, Peter C. ;
Grof, Paul ;
Rasgon, Natalie ;
Alda, Martin ;
Marsh, Wendy ;
Sagduyu, Kemal ;
Schmid, Rita ;
Adli, Mazda .
PSYCHOLOGICAL MEDICINE, 2008, 38 (07) :1069-1071
[4]   Phase advance is an actimetric correlate of antidepressant response to sleep deprivation and light therapy in bipolar depression [J].
Benedetti, Francesco ;
Dallaspezia, Sara ;
Fulgosi, Mara Cigala ;
Barbini, Barbara ;
Colombo, Cristina ;
Smeraldi, Enrico .
CHRONOBIOLOGY INTERNATIONAL, 2007, 24 (05) :921-937
[5]   Melatonin, sleep disturbance and cancer risk [J].
Blask, David E. .
SLEEP MEDICINE REVIEWS, 2009, 13 (04) :257-264
[6]  
Brainard GC, 2001, J NEUROSCI, V21, P6405
[7]   First do no harm: Managing antihistamine impairment in patients with allergic rhinitis [J].
Casale, TB ;
Blaiss, MS ;
Gelfand, E ;
Gilmore, T ;
Harvey, PD ;
Hindmarch, I ;
Simons, FER ;
Spangler, DL ;
Szefler, SJ ;
Terndrup, TE ;
Waldman, SA ;
Weiler, J ;
Wong, DE .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2003, 111 (05) :S835-S842
[8]   Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN [J].
Dacey, DM ;
Liao, HW ;
Peterson, BB ;
Robinson, FR ;
Smith, VC ;
Pokorny, J ;
Yau, KW ;
Gamlin, PD .
NATURE, 2005, 433 (7027) :749-754
[9]   Dose-response effects of cognitive-behavioral insomnia therapy: A randomized clinical trial [J].
Edinger, Jack D. ;
Wohlgemuth, William K. ;
Radtke, Rodney A. ;
Coffman, Cynthia J. ;
Carney, Colleen E. .
SLEEP, 2007, 30 (02) :203-212
[10]   Broad role for melanopsin in nonvisual photoreception [J].
Gooley, JJ ;
Lu, J ;
Fischer, D ;
Saper, CB .
JOURNAL OF NEUROSCIENCE, 2003, 23 (18) :7093-7106