Clinical utility of contrast-enhanced spectral mammography as an adjunct for tomosynthesis-detected architectural distortion

被引：46

作者：

Patel, Bhavika K. ^{[1
]}

Naylor, Michelle E. ^{[1
]}

Kosiorek, Heidi E. ^{[3
]}

Lopez-Alvarez, Yania M. ^{[1
]}

Miller, Adrian M. ^{[1
]}

Pizzitola, Victor J. ^{[1
]}

Pockaj, Barbara A. ^{[2
]}

机构：

[1] Mayo Clin Hosp, Dept Radiol, 5777 E Mayo Blvd, Phoenix, AZ 85054 USA

[2] Mayo Clin Hosp, Div Gen Surg, Phoenix, AZ 85054 USA

[3] Mayo Clin, Biostat, Scottsdale, AZ USA

来源：

CLINICAL IMAGING | 2017年 / 46卷

关键词：

Architectural distortion; Breast imaging; CESM; Contrast-enhanced spectral mammography; BACKGROUND PARENCHYMAL ENHANCEMENT; DIGITAL BREAST TOMOSYNTHESIS; MAGNETIC-RESONANCE MAMMOGRAPHY; CORE NEEDLE-BIOPSY; PATHOLOGICAL CORRELATION; MENSTRUAL-CYCLE; CANCER RISK; MRI IMPACT; LESIONS; MALIGNANCY;

D O I：

10.1016/j.clinimag.2017.07.003

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Objective: Supplement tomosynthesis-detected architectural distortions (AD) with CESM to better characterize malignant vs benign lesions. Methods: Retrospective review CESM prior to biopsied AD. Pathology: benign, radial scar, or malignant. Results: 49 lesions (45 patients). 29 invasive cancers, 1 DCIS (range, 0.4-4.7 cm); 9 radial scars; 10 benign. 37 (75.5%) ADs had associated enhancement. PPV 78.4% (29/37), sensitivity 96.7% (29/30); specificity, 57.9% (11/19); NPV, 91.7% (11/12). False-positive rate 21.6% (8/37); false-negative rate, 83% (1/12). Accuracy 81.6% (40/49). Conclusions: High sensitivity and NPV of CESM in patients with AD is promising as an adjunct tool in diagnosing malignancy and avoiding unnecessary biopsy, respectively. (C) 2017 Elsevier Inc. All rights reserved.

引用

页码：44 / 52

页数：9

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