New insights and tools to combat leprosy nerve damage

被引:0
作者
Ottenhoff, Tom H. M. [1 ]
机构
[1] Leiden Univ, Med Ctr, Dept Infect Dis, Leiden, Netherlands
关键词
HUMAN SCHWANN-CELLS; MYCOBACTERIUM-LEPRAE; REVERSAL REACTIONS; TNF-ALPHA; DEMYELINATION; EXPRESSION; MECHANISM;
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
引用
收藏
页码:334 / 337
页数:4
相关论文
共 10 条
  • [1] KHANOLKARYOUNG S, 1995, CLIN EXP IMMUNOL, V99, P196, DOI 10.1111/j.1365-2249.1995.tb05532.x
  • [2] Lockwood DNJ, 2000, LEPROSY REV, V71, pS111
  • [3] TLR6-Driven Lipid Droplets in Mycobacterium leprae-Infected Schwann Cells: Immunoinflammatory Platforms Associated with Bacterial Persistence
    Mattos, Katherine A.
    Oliveira, Viviane G. C.
    D'Avila, Heloisa
    Rodrigues, Luciana S.
    Pinheiro, Roberta O.
    Sarno, Euzenir N.
    Pessolani, Maria Cristina V.
    Bozza, Patricia T.
    [J]. JOURNAL OF IMMUNOLOGY, 2011, 187 (05) : 2548 - 2558
  • [4] Expression of toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy
    Oliveira, RB
    Ochoa, MT
    Sieling, PA
    Rea, TH
    Rambukkana, A
    Sarno, EN
    Modlin, RL
    [J]. INFECTION AND IMMUNITY, 2003, 71 (03) : 1427 - 1433
  • [5] Contact-dependent demyelination by Mycobacterium leprae in the absence of immune cells
    Rambukkana, A
    Zanazzi, G
    Tapinos, N
    Salzer, JL
    [J]. SCIENCE, 2002, 296 (5569) : 927 - 931
  • [6] Mycobacterium leprae-specific, HLA class II-restricted killing of human Schwann cells by CD4+ Th1 cells:: A novel immunopathogenic mechanism of nerve damage in leprosy
    Spierings, E
    de Boer, T
    Wieles, B
    Adams, LB
    Marani, E
    Ottenhoff, THM
    [J]. JOURNAL OF IMMUNOLOGY, 2001, 166 (10) : 5883 - 5888
  • [7] ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli
    Tapinos, Nikos
    Ohnishi, Makoto
    Rambukkana, Anura
    [J]. NATURE MEDICINE, 2006, 12 (08) : 961 - 966
  • [8] Expression of metalloproteinases (MMP-2, MMP-9, and TACE) and TNF-α in the nerves of leprosy patients
    Teles, Rosane M. B.
    Antunes, Sergio L. G.
    Jardim, Marcia R.
    Oliveira, Ariane L.
    Nery, Jose C.
    Sales, Ana M.
    Sampaio, Elizabeth P.
    Shubayev, Veronica
    Sarno, Euzenlr N.
    [J]. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2007, 12 (03) : 195 - 204
  • [9] Van Brakel WH, 2000, LEPROSY REV, V71, pS146
  • [10] Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2, macrophages subvert, immunity to (myco)bacteria
    Verreck, FAW
    de Boer, T
    Langenberg, DML
    Hoeve, MA
    Kramer, M
    Vaisberg, E
    Kastelein, R
    Kolk, A
    de Waal-Malefyt, R
    Ottenhoff, THM
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (13) : 4560 - 4565