Ion mobility separation of deprotonated oligosaccharide isomers - evidence for gas-phase charge migration

被引：57
作者：
Struwe, W. B. [1 ]
Baldauf, C. [2 ]
Hofmann, J. [2 ]
Rudd, P. M. [1 ]
Pagel, K. [2 ,3 ]
机构：
[1] Natl Inst Bioproc Res & Training, Fosters Ave, Dublin, Ireland
[2] Max Planck Gesell, Fritz Haber Inst, Faradayweg 4-6, D-14195 Berlin, Germany
[3] Free Univ Berlin, Inst Chem & Biochem, Takustr 3, D-14195 Berlin, Germany
来源：
CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 83期
基金：
英国生物技术与生命科学研究理事会;
关键词：
COLLISION CROSS-SECTIONS; N-LINKED GLYCANS; MASS-SPECTROMETRY; HUMAN-MILK; FRAGMENTATION; ELECTROSPRAY; DEPENDENCE; ADDUCTS; CATIONS;
D O I：
10.1039/c6cc06247d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
There has been increasing evidence that certain isomeric glycans can be separated efficiently by ion mobility-mass spectrometry when deprotonated ions are analyzed. To better understand the fundamentals behind these separations, we here investigate the impact of ionisation mode and adduct formation using IM-MS, density-functional theory and ab initio molecular dynamics.
引用
收藏
页码：12353 / 12356
页数：4
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