Highly Convergent Synthesis of Chiral Bicyclophosphinates by Domino Hydrophosphinylation/Michael/Michael Reaction

被引：10

作者：

Fourgeaud, Pierre ^{[1
]}

Dayde, Benedicte ^{[1
]}

Volle, Jean-Noel ^{[1
]}

Vors, Jean-Pierre ^{[2
]}

Van der Lee, Arie ^{[3
]}

Pirat, Jean-Luc ^{[1
]}

Virieux, David ^{[1
]}

机构：

[1] ENSCM, Inst Charles Gerhardt, UMR 5253, AM2N, F-34296 Montpellier, France

[2] Bayer CropSci SAS, F-69263 Lyon 09, France

[3] Univ Montpellier 2, IEM, F-34095 Montpellier 5, France

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 19期

关键词：

ENANTIOSELECTIVE HYDROPHOSPHONYLATION; CASCADE REACTIONS; PHOSPHINE OXIDES; ALLENYLPHOSPHONATES; DERIVATIVES; ALDEHYDES; PRECURSORS; CHEMISTRY; PRODUCTS; ALCOHOLS;

D O I：

10.1021/ol2019345

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diastereoselective domino reactions of iminoalcohols and allenyl H-phosphinates produce chiral phosphorus bicycles in a regio- and stereoselective fashion. A predictive model for diastereoselection is used for these new chiral phosphinic esters.

引用

页码：5076 / 5079

页数：4

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