Early SARS-CoV-2-associated acute transverse myelitis: A case for neurotropism?

被引:5
作者
Lu, Irene F. [1 ]
Cornish, Jack S. [1 ]
Ashok, Aadith [1 ]
Chen, Siew Kar [1 ]
Athan, Eugene [1 ,2 ]
Hughes, Andrew [1 ]
机构
[1] Univ Hosp Geelong, Barwon Hlth, Ryrie St, Geelong, Vic, Australia
[2] Deakin Univ, Sch Med, Geelong, Vic, Australia
关键词
COVID-19; myelitis; neurotropism; SARS-COV-2;
D O I
10.1111/joim.13542
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There are increasing reports of immune-mediated and para-infectious syndromes beyond the well-known respiratory manifestations of severe-acute-respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the spectrum of severe neurological sequelae of SARS-CoV-2 remains undefined. We present the case of a 66-year-old female with rapidly progressive lower limb neurology 3 days post SARS-CoV-2 infection. Clinical and radiological findings were in keeping with transverse myelitis and treatment success was achieved with methylprednisolone and remdesivir. This report will discuss the associations between SARS-CoV-2 and acute transverse myelitis. We believe this is one of few described cases of early SARS-CoV-2-associated transverse myelitis secondary to neurotropism and the first successfully treated with the inclusion of remdesivir in the therapeutic regimen.
引用
收藏
页码:679 / 683
页数:5
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