Mucinous Cancer of the Ovary: Overview and Current Status

被引：84

作者：

Babaier, Abdulaziz ^{[1
]}

Ghatage, Prafull ^{[2
]}

机构：

[1] King Fahad Specialist Hosp, Dept Gynecol Oncol, Dammam 32253, Saudi Arabia

[2] Tom Baker Canc Clin, Dept Gynecol Oncol, Calgary, AB T2N 4N2, Canada

来源：

DIAGNOSTICS | 2020年 / 10卷 / 01期

关键词：

mucinous ovarian carcinoma; metastatic mucinous carcinoma; genomic profile; surgery; chemotherapy; targeted therapy; HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY; PLACENTAL ALKALINE-PHOSPHATASE; RECURRENT EPITHELIAL OVARIAN; HUMAN CHORIONIC-GONADOTROPIN; HEAVILY PRETREATED PATIENTS; LYMPH-NODE METASTASIS; TERM-FOLLOW-UP; PHASE-III; BORDERLINE TUMORS; INTESTINAL-TYPE;

D O I：

10.3390/diagnostics10010052

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Mucinous ovarian cancer (MOC) is a rare subtype of epithelial ovarian carcinoma (EOC). Whereas all EOC subtypes are addressed in the same way, MOC is a distinct entity. Appreciating the pathological features and genomic profile of MOC may result in the improvement in management and, hence, the prognosis. Distinguishing primary MOC from metastatic mucinous carcinoma can be challenging but is essential. Early-stage MOC carries an excellent prognosis, with advanced disease having a poor outcome. Surgical management plays an essential role in the early stage and in metastatic disease. Chemotherapy is usually administered for stage II MOC and beyond. The standard gynecology protocol is frequently used, but gastrointestinal regimens have also been administered. As MOC is associated with multiple molecular alterations, targeted therapy could be the answer to treat this disease.

引用

页数：16

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