Almost all irritable bowel syndromes are post-infectious and respond to probiotics: Consensus issues

被引：12
|
作者：
Cuomo, Rosario [1 ]
Savarese, Maria Flavia [1 ]
Gargano, Rosalba [1 ]
机构：
[1] Univ Naples Federico II, Gastroenterol Unit, Dept Clin & Expt Med, IT-80131 Naples, Italy
来源：
DIGESTIVE DISEASES | 2007年 / 25卷 / 03期
关键词：
irritable bowel syndrome; functional bowel disorders; post-infectious irritable bowel syndrome; probiotics;
D O I：
10.1159/000103893
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Several reports have described post-infectious irritable bowel syndrome ( Pi-IBS), while many animal and human studies have shown the presence of increased infiltration of inflammatory cells and hyperplasia of enterochromaffin cells in the intestinal mucosa after acute gastroenteritis. The potential value of probiotic bacteria in restoring normal gut function has been demonstrated by animal models of Pi-IBS. In humans, Pi-IBS can be prevented utilizing probiotics to reduce the duration of acute gastroenteritis, despite the variable efficacy shown in randomized control trials evaluating unspecified IBS. Here, advances in the pathophysiology supporting the post-infectious hypothesis are considered. In addition, the current role of probiotics in the management of Pi-IBS is discussed. Copyright (c) 2007 S. Karger AG, Basel
引用
收藏
页码：241 / 244
页数：4
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