Effect of dietary esterified glucomannan on performance, serum biochemistry and haematology in broilers exposed to aflatoxin

被引:83
作者
Basmacioglu, H [1 ]
Oguz, H
Ergul, M
Col, R
Birdane, YO
机构
[1] Agean Univ, Dept Anim Sci, Fac Agr, TR-35100 Izmir, Turkey
[2] Selcuk Univ, Fac Med Vet, Dept Pharmacol & Toxicol, Konya, Turkey
[3] Selcuk Univ, Fac Med Vet, Dept Physiol, Konya, Turkey
[4] Afyon Kocatepe Univ, Fac Med Vet, Dept Pharmacol & Toxicol, Afyon, Turkey
关键词
aflatoxin; esterified glucomannan; broiler; prevention;
D O I
10.17221/3992-CJAS
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
The amelioration of aflatoxicosis in broiler chickens was examined by feeding two concentrations of yeast component (esterified glucomannan; EG). EG, incorporated into the diet at 0.5 and 1 g/kg, was evaluated for its ability to reduce the detrimental effects of 2 mg total aflatoxin (AF; 82.72% AFB(1), 5.50% AFB(2), 10.20% AFG(1) and 1.58% AFG(2)) in diet on growing broiler chicks from 1 to 21 d of age. A total of 240 male broiler chicks (Ross-308) were divided into 6 treatment groups [control, AF, EG (0.5 g/kg), AF plus EG (0.5 g/kg), EG (1 g/kg), and AF plus EG (1 g/kg)]. Compared to the control, AF treatment significantly decreased body weight gain from week 2 onwards. AF treatment also caused significant decreases in serum total protein, albumin, total cholesterol, triglyceride, glucose, inorganic phosphorus, creatinine levels and alanine-aminotransferase (ALAT) activity but increased the aspartate-aminotransferase (ASAT) activity. Red blood cell, haematocrit, haemoglobin, thrombocyte, and lymphocyte counts and tibial crude ash levels were significantly reduced by AF treatment, while significant increases were seen in heterophil counts. The addition of EG (I g/kg) to an AF-containing diet significantly improved the adverse effects of AF on haematological parameters, total protein, albumin values and ASAT activity. EG (I g/kg) also partially improved body weight gains (59%) and the other biochemical parameters influenced by AF treatment. The addition of EG (both 0.5 and 1 g/kg) to the AF-free diet did not cause any considerable changes in the investigated values. These results clearly indicated that EG (I g/kg) addition effectively diminished the adverse effects of AF on the investigated values. Also, the higher dietary concentration of EG (I g/kg) was found more effective than the lower concentration (0.5 g/kg) against the adverse effects of AF on the variables investigated in this study.
引用
收藏
页码:31 / 39
页数:9
相关论文
共 45 条
[1]  
[Anonymous], 1991, PUBLICATIONS, V9610, P1
[2]   Efficacy of esterified glucomannan to counteract mycotoxicosis in naturally contaminated feed on performance and serum biochemical and hematological parameters in broilers [J].
Aravind, KL ;
Patil, VS ;
Devegowda, G ;
Umakantha, B ;
Ganpule, SP .
POULTRY SCIENCE, 2003, 82 (04) :571-576
[3]   Detoxification of mycotoxin-contaminated food and feed by microorganisms [J].
Bata, A ;
Lásztity, R .
TRENDS IN FOOD SCIENCE & TECHNOLOGY, 1999, 10 (6-7) :223-228
[4]  
DEVEGOWDA G, 1997, FEEDING TIMES
[5]  
Diaz Duarte E, 2002, Mycopathologia, V156, P223
[6]   Effects of T-2 toxin, zeolite and Mycosorb on antioxidant systems of growing quail [J].
Dvorska, JE ;
Surai, PF .
ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 2001, 14 (12) :1752-1757
[7]   Dietary mannan-oligosaccharides and their effect on chicken caecal microflora in relation to Salmonella Enteritidis colonization [J].
Fernandez, F ;
Hinton, M ;
Van Gils, B .
AVIAN PATHOLOGY, 2002, 31 (01) :49-58
[8]  
Fritts C. A., 2003, International Journal of Poultry Science, V2, P19
[9]   AFLATOXICOSIS ALTERS AVIAN RENAL-FUNCTION, CALCIUM, AND VITAMIN-D METABOLISM [J].
GLAHN, RP ;
BEERS, KW ;
BOTTJE, WG ;
WIDEMAN, RF ;
HUFF, WE ;
THOMAS, W .
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH, 1991, 34 (03) :309-321
[10]   EFFICACY OF ZEOLITIC ORE COMPOUNDS ON THE TOXICITY OF AFLATOXIN TO GROWING BROILER-CHICKENS [J].
HARVEY, RB ;
KUBENA, LF ;
ELISSALDE, MH ;
PHILLIPS, TD .
AVIAN DISEASES, 1993, 37 (01) :67-73