Effect of cervical conization on pregnancy outcome of in-vitro fertilization/intracytoplasmic sperm injection treatment: a retrospective cohort study

被引:2
作者
Ding, Lingling [1 ,2 ,3 ]
Li, Miao [1 ,2 ,3 ]
Yan, Lei [1 ,2 ,3 ]
Tang, Rong [1 ,2 ,3 ]
Chen, Zi-Jiang [1 ,2 ,3 ]
机构
[1] Shandong Univ, Shandong Prov Hosp, Shandong Prov Key Lab Reprod Med, Ctr Reprod Med, Jinan, Peoples R China
[2] Natl Res Ctr Assisted Reprod Technol & Reprod Gen, Jinan, Peoples R China
[3] Minist Educ, Key Lab Reprod Endocrinol, Jinan, Peoples R China
基金
中国国家自然科学基金;
关键词
Cervical conization; In vitro fertilization; Pregnancy; Cohort study; ELECTROSURGICAL EXCISION PROCEDURE; COLD-KNIFE CONIZATION; INTRAEPITHELIAL NEOPLASIA; LESIONS; RISK; DELIVERY; PRETERM; CANCER;
D O I
10.12891/ceog3028.2016
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Aims: To investigate the effect of cervical conization on the outcome of in-vitro fertilization/intracytoplasmic sperm injection IVF/ICSI) treatment. Materials and Alethods: The authors performed a retrospective, database-searched cohort study based on patients undergoing controlled ovarian hyperstimulation and IVF/ICSI between 2009 and 2013 in the present hospital. Cervical intraepithelial neoplasia (CIN) or cervical cancer was carefully confirmed by transvaginal ultrasound, hysteroscopy, and biopsy. High-quality case-control study with strict inclusion criteria was conducted. The authors analyzed basic characters and main IVF/ICSI outcomes between both groups. Results: The authors included 48 patients with a history of cervical conization who underwent IVF/ICSI and control group without cervical conization. No significant differences were found in IVF/ICSI outcomes between both groups. No obvious evidence was found indicating that cervical stenosis could impact IVF operation. Conclusions: The present results suggest that cervical conization does not affect IVF/ICSI outcomes. Patients can receive cervical conization before undertaking assisted reproductive technology.
引用
收藏
页码:546 / 549
页数:4
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