Nanomaterial Applications in Photothermal Therapy for Cancer

被引:340
作者
Doughty, Austin C. V. [1 ]
Hoover, Ashley R. [1 ]
Layton, Elivia [1 ]
Murray, Cynthia K. [2 ]
Howard, Eric W. [3 ]
Chen, Wei R. [1 ]
机构
[1] Univ Cent Oklahoma, Biophoton Res Lab, Ctr Interdisciplinary Biomed Educ & Res, Coll Math & Sci, Edmond, OK 73034 USA
[2] Univ Cent Oklahoma, Dept Math & Stat, Coll Math & Sci, Edmond, OK 73034 USA
[3] Univ Oklahoma, Hlth Sci Ctr, Dept Cell Biol, Oklahoma City, OK 73104 USA
基金
美国国家卫生研究院;
关键词
cancer; metastatic; photothermal therapy; ablation; nanomaterials; combination therapy; MODIFIED GOLD NANORODS; CARBON NANOTUBES; SURFACE-CHEMISTRY; TUMOR ABLATION; DRUG-DELIVERY; GRAPHENE; IMMUNOTHERAPY; NANOPARTICLE; HYPERTHERMIA; MODALITY;
D O I
10.3390/ma12050779
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
As a result of their unique compositions and properties, nanomaterials have recently seen a tremendous increase in use for novel cancer therapies. By taking advantage of the optical absorption of near-infrared light, researchers have utilized nanostructures such as carbon nanotubes, gold nanorods, and graphene oxide sheets to enhance photothermal therapies and target the effect on the tumor tissue. However, new uses for nanomaterials in targeted cancer therapy are coming to light, and the efficacy of photothermal therapy has increased dramatically. In this work, we review some of the current applications of nanomaterials to enhance photothermal therapy, specifically as photothermal absorbers, drug delivery vehicles, photoimmunological agents, and theranostic tools.
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页数:14
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