Review on Nanoparticles and Nanostructured Materials: Bioimaging, Biosensing, Drug Delivery, Tissue Engineering, Antimicrobial, and Agro-Food Applications

被引:307
作者
Harish, Vancha [1 ]
Tewari, Devesh [1 ]
Gaur, Manish [2 ]
Yadav, Awadh Bihari [2 ]
Swaroop, Shiv [3 ]
Bechelany, Mikhael [4 ]
Barhoum, Ahmed [5 ,6 ]
机构
[1] Lovely Profess Univ, Sch Pharmaceut Sci, Phagwara 144401, Punjab, India
[2] Univ Allahabad, Ctr Biotechnol, Prayagraj 211002, Uttar Pradesh, India
[3] Cent Univ Rajasthan, Dept Biochem, Ajmer 305817, India
[4] Univ Montpellier, CNRS, ENSCM, Inst Europeen Membranes,IEM,UMR 5635, F-34730 Montpellier, France
[5] NanoStruc Res Grp, Chem Dept, Fac Sci, Cairo 11795, Egypt
[6] Dublin City Univ, Sch Chem Sci, Natl Ctr Sensor Res, Dublin D09 Y074, Ireland
关键词
nanostructures; nanomaterials; drug delivery systems; tissue-engineered scaffolds; wound dressings; skincare; risks and toxicities; market and regulations; IRON-OXIDE NANOPARTICLES; CONJUGATED POLYMER NANOPARTICLES; TITANIUM-DIOXIDE NANOPARTICLES; COATED FE3O4 NANOPARTICLES; HOT-INJECTION SYNTHESIS; SUPEROXIDE-DISMUTASE; SILVER NANOPARTICLES; GOLD NANOPARTICLES; QUANTUM DOTS; GENE-THERAPY;
D O I
10.3390/nano12030457
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In the last few decades, the vast potential of nanomaterials for biomedical and healthcare applications has been extensively investigated. Several case studies demonstrated that nanomaterials can offer solutions to the current challenges of raw materials in the biomedical and healthcare fields. This review describes the different nanoparticles and nanostructured material synthesis approaches and presents some emerging biomedical, healthcare, and agro-food applications. This review focuses on various nanomaterial types (e.g., spherical, nanorods, nanotubes, nanosheets, nanofibers, core-shell, and mesoporous) that can be synthesized from different raw materials and their emerging applications in bioimaging, biosensing, drug delivery, tissue engineering, antimicrobial, and agro-foods. Depending on their morphology (e.g., size, aspect ratio, geometry, porosity), nanomaterials can be used as formulation modifiers, moisturizers, nanofillers, additives, membranes, and films. As toxicological assessment depends on sizes and morphologies, stringent regulation is needed from the testing of efficient nanomaterials dosages. The challenges and perspectives for an industrial breakthrough of nanomaterials are related to the optimization of production and processing conditions.
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页数:43
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