Effect of petroleum ether fractions of Morinda lucida on Plasmodium berghei berghei in mice

被引：10
|
作者：
Awe, SO [1 ]
Makinde, JM [1 ]
机构：
[1] Univ Ibadan, Coll Med, Dept Pharmacol & Therapeut, Ibadan, Nigeria
来源：
PHARMACEUTICAL BIOLOGY | 1998年 / 36卷 / 04期
关键词：
Morinda lucida; antimalarial; fractions; Plasmodium berghei berghei; schizontocidal;
D O I：
10.1076/phbi.36.4.301.4581
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Efforts were made to evaluate the antimalarial activity of fractions obtained from Morinda lucida, a local medicinal plant commonly used against fever. The March and June samples of the plant were screened against Plasmodium berghei berghei in mice. The fractions demonstrated schizontocidal activity against early infection with fraction A of the March and June samples giving the highest chemosuppression. The fractions showed less activity when evaluated for repository effect, while some of the fractions of the samples proved active against established infections.
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页码：301 / 304
页数：4
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