Disseminated Strongyloides stercoralis Infection in HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma

被引：26

作者：

Stewart, Donn M. ^{[1
]}

Ramanathan, Roshan ^{[2
]}

Mahanty, Siddhartha ^{[2
]}

Fedorko, Daniel P. ^{[3
]}

Janik, John E.

Morris, John C.

机构：

[1] NCI, Metab Branch, Ctr Canc Res, Mark O Hatfield Clin Res Ctr, Bethesda, MD 20892 USA

[2] NIAID, Parasit Dis Lab, Bethesda, MD 20892 USA

[3] NIH, Microbiol Serv, Warren G Magnuson Clin Ctr, Bethesda, MD 20892 USA

来源：

ACTA HAEMATOLOGICA | 2011年 / 126卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Adult T-cell leukemia; Alemtuzumab; Corticosteroid; Disseminated Strongyloides; HTLV-1; Human T-cell lymphotropic virus type-1; EOSINOPHIL COUNT; DIAGNOSIS; HTLV-1; IVERMECTIN; THIABENDAZOLE; ALBENDAZOLE; EXPANSION; RESPONSES; CARRIERS; ANTIGEN;

D O I：

10.1159/000324799

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 55-year-old woman with human T-cell lymphotropic virus type-1 (HTLV-1)-associated adult T-cell leukemia (ATL) and a history of previously treated Strongyloides stercoralis infection received anti-CD52 monoclonal antibody therapy with alemtuzumab on a clinical trial. After an initial response, she developed ocular involvement by ATL. Alemtuzumab was stopped and high-dose corticosteroid therapy was started to palliate her ocular symptoms. Ten days later, the patient developed diarrhea, vomiting, fever, cough, skin rash, and a deteriorating mental status. She was diagnosed with disseminated S. stercoralis. Corticosteroids were discontinued and the patient received anthelmintic therapy with ivermectin and albendazole with complete clinical recovery. Copyright (C) 2011 S. Karger AG, Basel

引用

页码：63 / 67

页数：5

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