A response to the two faces of autophagy in DCIS

被引：60

作者：

Espina, Virginia ^{[1
]}

Liotta, Lance A. ^{[1
]}

机构：

[1] George Mason Univ, Ctr Appl Prote & Mol Med, Manassas, VA 20110 USA

来源：

NATURE REVIEWS CANCER | 2011年 / 11卷 / 08期

关键词：

CANCER; CHLOROQUINE; DEGRADATION; RESISTANCE; THERAPY;

D O I：

10.1038/nrc2950-c2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：618 / 618

页数：1

共 15 条

[1] Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma [J].

Amaravadi, Ravi K. ;

Yu, Duonan ;

Lum, Julian J. ;

Bui, Thi ;

Christophorou, Maria A. ;

Evan, Gerard I. ;

Thomas-Tikhonenko, Andrei ;

Thompson, Craig B. .

JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (02) :326-336

[2] Institutional experience with chloroquine as an adjuvant to the therapy for glioblastoma multiforme [J].

Briceno, Eduardo ;

Calderon, Alejandra ;

Sotelo, Julio .

SURGICAL NEUROLOGY, 2007, 67 (04) :388-391

[3] Clinical pharmacokinetics and metabolism of chloroquine - Focus on recent advancements [J].

Ducharme, J ;

Farinotti, R .

CLINICAL PHARMACOKINETICS, 1996, 31 (04) :257-274

[4] What is the malignant nature of human ductal carcinoma in situ? [J].

Espina, Virginia ;

Liotta, Lance A. .

NATURE REVIEWS CANCER, 2011, 11 (01) :68-75

[5] Malignant Precursor Cells Pre-Exist in Human Breast DCIS and Require Autophagy for Survival [J].

Espina, Virginia ;

Mariani, Brian D. ;

Gallagher, Rosa I. ;

Tran, Khoa ;

Banks, Stacey ;

Wiedemann, Joy ;

Huryk, Heather ;

Mueller, Claudius ;

Adamo, Luana ;

Deng, Jianghong ;

Petricoin, Emanuel F., III ;

Pastore, Lucia ;

Zaman, Syed ;

Menezes, Geetha ;

Mize, James ;

Johal, Jasbir ;

Edmiston, Kirsten ;

Liotta, Lance A. .

PLOS ONE, 2010, 5 (04)

[6] Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis [J].

Maclean, Kirsteen H. ;

Dorsey, Frank C. ;

Cleveland, John L. ;

Kastan, Michael B. .

JOURNAL OF CLINICAL INVESTIGATION, 2008, 118 (01) :79-88

[7] Autophagy suppression promotes apoptotic cell death in response to inhibition of the PI3K-mTOR pathway in pancreatic adenocarcinoma [J].

Mirzoeva, Olga K. ;

Hann, Byron ;

Hom, Yun K. ;

Debnath, Jayanta ;

Aftab, Dana ;

Shokat, Kevan ;

Korn, W. Michael .

JOURNAL OF MOLECULAR MEDICINE-JMM, 2011, 89 (09) :877-889

[8] Affinity and Avidity in Antibody-Based Tumor Targeting [J].

Rudnick, Stephen I. ;

Adams, Gregory P. .

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2009, 24 (02) :155-161

[9] Autophagy facilitates the progression of ERα-positive breast cancer cells to antiestrogen resistance [J].

Schoenlein, Patricia V. ;

Periyasamy-Thandavan, Sudharsan ;

Samaddar, Julia S. ;

Jackson, William H. ;

Barrett, John T. .

AUTOPHAGY, 2009, 5 (03) :400-403

[10]

SEGLEN PO, 1980, MOL PHARMACOL, V18, P468

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