All-Cause Mortality Following an Acute Coronary Syndrome: 12-Year Follow-Up of: the Comprehensive 2002 New Zealand Acute Coronary Syndrome Audit

被引：20

作者：

Ellis, Chris J. ^{[1
]}

Gamble, Greg D. ^{[2
]}

Williams, Michael J. A. ^{[3
]}

Matsis, Phil ^{[4
]}

Elliott, John M. ^{[5
]}

Devlin, Gerry ^{[6
]}

Mann, Stewart ^{[4
]}

French, John K. ^{[7
]}

White, Harvey D. ^{[1
]}

Burgoyne, P. ^{[8
]}

August, S. ^{[8
]}

Wong, B. ^{[9
]}

O'Keefe, K. ^{[9
]}

Hart, H. ^{[10
]}

Wickham, J. ^{[10
]}

Ellis, C. ^{[11
]}

Gamble, G. ^{[11
]}

Benjamin, W. ^{[11
]}

Clarke, T. ^{[12
]}

French, J. ^{[13
]}

White, H. ^{[13
]}

Williams, B. ^{[13
]}

Maslowski, A. ^{[14
]}

Ko, A. ^{[15
]}

Lund, M. ^{[15
]}

Oettli, H. ^{[15
]}

Lennane, J. ^{[16
]}

Aftabuzzaman ^{[16
]}

Tisch, J. ^{[17
]}

Porter, G. ^{[17
]}

Watts, V. ^{[17
]}

Braid, J. ^{[17
]}

Devlin, G. ^{[6
]}

Penney, D. ^{[6
]}

Edwards, E. ^{[18
]}

Garner, D. ^{[18
]}

Logan, K. ^{[19
]}

Morley, A. ^{[19
]}

Reeve, P. ^{[20
,21
,24
]}

Kanan, F. ^{[20
]}

Reeve, P. ^{[20
,21
,24
]}

Pusupati, J. ^{[21
]}

Ludbrook, A. ^{[22
]}

Aitcheson, F. ^{[23
]}

Weytmans, K. ^{[23
]}

Reeve, P. ^{[20
,21
,24
]}

Shepherd, R. ^{[24
]}

Ternouth, I. ^{[25
]}

Luke, R. ^{[26
]}

Mackenzie, J. ^{[26
]}

机构：

[1] Auckland City Hosp, Dept Cardiol, Auckland, New Zealand

[2] Univ Auckland, Dept Med, Auckland, New Zealand

[3] Dunedin Publ Hosp, Dunedin, New Zealand

[4] Wellington Hosp, Wellington, New Zealand

[5] Christchurch Hosp, Christchurch, New Zealand

[6] Waikato Hosp, Hamilton, New Zealand

[7] Liverpool Hosp, Sydney, NSW, Australia

[8] Kawakawa Hosp, Kawakawa, New Zealand

[9] Whangarei Hosp, Whangarei, New Zealand

[10] North Shore Hosp, Auckland, New Zealand

[11] Auckland Hosp, Auckland, New Zealand

[12] Mercy Private Hosp, Auckland, New Zealand

[13] Green Lane Hosp, Auckland, New Zealand

[14] Ascot Private Hosp, Auckland, New Zealand

[15] Middlemore Hosp, Auckland, New Zealand

[16] Thames Hosp, Thames, New Zealand

[17] Tauranga Hosp, Tauranga, New Zealand

[18] Whakatane Hosp, Whakatane, New Zealand

[19] Rotorua Hosp, Rotorua, New Zealand

[20] Tokoroa Hosp, Tokoroa, New Zealand

[21] Te Kuiti Hosp, Te Kuiti, New Zealand

[22] Taupo Hosp, Taupo, New Zealand

[23] Gisborne Hosp, Gisborne, New Zealand

[24] Taumarunui Hosp, Taumarunui, New Zealand

[25] New Plymouth Hosp, New Plymouth, New Zealand

[26] Hastings Hosp, Hastings, New Zealand

[27] Wanganui Hosp, Whanganui, New Zealand

[28] Palmerston North Hosp, Palmerston North, New Zealand

[29] Masterton Hosp, Masterton, New Zealand

[30] Hutt Hosp, Lower Hutt, New Zealand

[31] Wakefield Private Hosp, Wellington, New Zealand

[32] Nelson Hosp, Nelson, New Zealand

[33] Blenheim Hosp, Blenheim, New Zealand

[34] Greymouth Hosp, Greymouth, New Zealand

[35] Ashburton Hosp, Ashburton, New Zealand

[36] Timaru Hosp, Timaru, New Zealand

[37] Oamaru Hosp, Oamaru, New Zealand

[38] Dunstan Hosp Clyde, Otago, New Zealand

[39] Dunedin Publ Hosp, Dunedin, New Zealand

[40] Invercargill Hosp, Invercargill, New Zealand

来源：

HEART LUNG AND CIRCULATION | 2019年 / 28卷 / 02期

关键词：

Acute coronary syndromes; Prognosis; Follow-up studies; Death; ACUTE MYOCARDIAL-INFARCTION; LONG-TERM MORTALITY; GLOBAL REGISTRY; MANAGEMENT; AUSTRALIA; OUTCOMES; IMPROVEMENT; SURVIVAL; HEALTH; CARE;

D O I：

10.1016/j.hlc.2017.10.015

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background To describe the long-term mortality of a complete national cohort of acute coronary syndrome (ACS) patients enrolled in 2002, to compare this with a national age, sex and Maori ethnicity matched population, and to assess the influence of baseline factors on the 12-year mortality. Methods We reviewed 721 patients with a discharge diagnosis of an ACS who were enrolled in the first New Zealand ACS audit group cohort over 14 days in May 2002. We matched the cohort to the national mortality database using each patient's unique national identity number. Results Over a median follow-up of 12.7 years of 721 patients discharged with an ACS, overall mortality was 52%: ST-elevation myocardial infarction (STEMI) (58%), non-ST-elevation myocardial infarction (NSTEMI) (61%) and unstable angina pectoris (UAP) (42%) patients, p < 0.0001. In an age-adjusted survival model, males had a 29% increased mortality rate compared to females with a hazard ratio of 1.29 (95% CI 1.04, 1.61, p = 0.019). Over 12 years there were 339 (47%) deaths, compared to 284 (39%) deaths observed in the matched population. The standardised mortality ratio for patients admitted with an ACS in New Zealand is 1.3 (95% CI 1.2, 1.5) with eight patients per 100 not surviving to 12 years compared to this matched population. Conclusion The high mortality rate in this ACS cohort is a stark reminder of the prognostic implications of a presentation with an ACS. It emphasises the on-going need for optimal management of these patients throughout every stage of their initial treatment and subsequent on-going care.

引用

页码：245 / 256

页数：12

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