The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability? -A Review

被引:6
作者
Feduniw, Stepan [1 ]
Gaca, Zuzanna [2 ]
Malinowska, Olga [3 ]
Brunets, Weronika [4 ]
Zgliczynska, Magdalena [5 ]
Wlodarczyk, Marta [6 ,7 ]
Wojcikiewicz, Anna [8 ]
Ciebiera, Michal [8 ]
机构
[1] Ctr Postgrad Med Educ, Dept Reprod Hlth, PL-01004 Warsaw, Poland
[2] Czerniakowski Hosp, PL-00739 Warsaw, Poland
[3] Med Univ Bialystok, Fac Med, PL-15089 Bialystok, Poland
[4] Lazarski Univ, Fac Med, PL-02662 Warsaw, Poland
[5] Ctr Postgrad Med Educ, Dept Obstet Perinatol & Neonatol, PL-01809 Warsaw, Poland
[6] Med Univ Warsaw, Fac Pharm, Dept Biochem & Pharmacogen, PL-02097 Warsaw, Poland
[7] Med Univ Warsaw, Ctr Preclin Res, PL-02097 Warsaw, Poland
[8] Ctr Postgrad Med Educ, Dept Obstet & Gynecol 2, PL-01809 Warsaw, Poland
关键词
previable PPROM; preterm rupture of membranes; PTB; preterm delivery; antibiotics; PRELABOR RUPTURE; RISK-FACTORS; ANTIBIOTIC REGIMENS; LATENCY PERIOD; HOME-CARE; OUTCOMES; PPROM; BIRTH; WOMEN; TOCOLYSIS;
D O I
10.3390/diagnostics12082025
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Preterm premature rupture of the membranes (PPROM) at the limit of viability is associated with low neonatal survival rates and a high rate of neonatal complications in survivors. It carries a major risk of maternal morbidity and mortality. The limit of viability can be defined as the earliest stage of fetal maturity when a fetus has a reasonable chance, although not a high likelihood, for extra-uterine survival. The study reviews available data on preventing preterm delivery caused by the previable PPROM, pregnancy latency, therapeutic options including the use of antibiotics and steroids, neonatal outcomes, and future directions and opportunities.
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页数:13
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