Is the Exhaled Breath Temperature Sensitive to Cigarette Smoking?

被引:6
作者
Carpagnano, Giovanna E. [1 ]
Ruggieri, Cinzia [1 ]
Scioscia, Giulia [1 ]
Lo Storto, Maria Maddalena [1 ]
Zoppo, Luigi [1 ]
Foschino-Barbaro, Maria P. [1 ]
机构
[1] Univ Foggia, Dept Med & Surg Sci, Inst Resp Dis, I-70121 Foggia, Italy
关键词
airways inflammation; cigarette smoking; exhaled breath temperature; non-invasive methods; smoking cessation; OBSTRUCTIVE PULMONARY-DISEASE; AIRWAY INFLAMMATION; INDIVIDUAL DEVICE; NITRIC-OXIDE; CESSATION; ASTHMA; MARKER; EXPOSURE; CHILDREN; FLUID;
D O I
10.3109/15412555.2016.1143458
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
The smoking habit is accompanied by an acute inflammatory response which follows tissue injury. It would be desirable to find a non-invasive inflammatory marker that would simplify the task of studying and monitoring smokers more simply and allow us to identify populations at risk of contracting Chronic Obstructive Pulmonary Disease (COPD). Today's expectations regarding research focus on issues ranging from inflammatory markers to those of exhaled breath temperature (EBT) are considerable. That said, although the EBT has been largely studied in asthma and COPD, there have not been any studies thus far that have analysed the effect of cigarette smoking on the EBT. Bearing this in mind, in this longitudinal study we aim to analyse the EBT in current smokers, monitor the effects both of cigarette smoking on EBT and of what happens after smoking cessation. Twenty-five (25) smokers (59.5 +/- 3.1 yrs, 12 M) who participated in a multi-disciplinary smoking cessation programme and 25 healthy never-smokers (58.7 +/- 2.9, 13 M) underwent EBT measurement. EBT values were higher in smokers before smoking (T0) than in never-smokers [34.6 (34.2-35) vs 33.2 (32.4-33.7)degrees C, p < 0.001. The smokers repeated measurement 5 minutes after smoking a cigarette (T1) and 2 hours after (T2). They repeated EBC measurement after 1week (T3) and then after 3 months (T4) from smoking cessation. EBT is higher in smokers compared to controls. EBT increases after cigarette smoking and progressively decreases with the increase of time from when the last cigarette was smoked. Thus, we can conclude that EBT is increased in smokers and also sensitive to the acute effect of cigarette smoke.
引用
收藏
页码:642 / 646
页数:5
相关论文
共 30 条
[1]   Chronic Obstructive Pulmonary Disease and Lung Cancer: New Molecular Insights [J].
Adcock, Ian M. ;
Caramori, Gaetano ;
Barnes, Peter J. .
RESPIRATION, 2011, 81 (04) :265-284
[2]   Clara cell secretory protein -: Levels in BAL fluid after smoking cessation [J].
Andersson, O ;
Cassel, TN ;
Sköld, CM ;
Eklund, A ;
Lund, J ;
Nord, M .
CHEST, 2000, 118 (01) :180-182
[3]   Increased nitric oxide metabolites in exhaled breath condensate after exposure to tobacco smoke [J].
Balint, B ;
Donnelly, LE ;
Hanazawa, T ;
Kharitonov, SA ;
Barnes, PJ .
THORAX, 2001, 56 (06) :456-461
[4]   Sputum and nasal lavage lung-specific biomarkers before and after smoking cessation [J].
Bouloukaki, Izolde ;
Tsiligianni, Ioanna G. ;
Tsoumakidou, Maria ;
Mitrouska, Ioanna ;
Prokopakis, Emmanuel P. ;
Mavroudi, Irene ;
Siafakas, Nikolaos M. ;
Tzanakis, Nikolaos .
BMC PULMONARY MEDICINE, 2011, 11
[5]   Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation [J].
Braber, Saskia ;
Henricks, Paul A. J. ;
Nijkamp, Frans P. ;
Kraneveld, Aletta D. ;
Folkerts, Gert .
RESPIRATORY RESEARCH, 2010, 11
[6]   Exhaled breath temperature in NSCLC: Could be a new non-invasive marker? [J].
Carpagnano, Giovanna E. ;
Lacedonia, Donato ;
Spanevello, Antonio ;
Martinelli, Domenico ;
Saliani, Valerio ;
Ruggieri, Cinzia ;
Foschino-Barbaro, Maria P. .
MEDICAL ONCOLOGY, 2014, 31 (05)
[7]   Time course of cigarette smoke-induced pulmonary inflammation in mice [J].
D'hulst, AI ;
Vermaelen, KY ;
Brusselle, GG ;
Joos, GF ;
Pauwels, RA .
EUROPEAN RESPIRATORY JOURNAL, 2005, 26 (02) :204-213
[8]   Patterns of Inflammatory Responses in Large and Small Airways in Smokers with and without Chronic Obstructive Pulmonary Disease [J].
Isajevs, Sergejs ;
Taivans, Immanuels ;
Svirina, Darja ;
Strazda, Gunta ;
Kopeika, Uldis .
RESPIRATION, 2011, 81 (05) :362-371
[9]  
Kasper DL., 2005, Principles of Internal Medicine, V16th
[10]   Exhaled breath temperature, a new biomarker in asthma control: A pilot study [J].
Melo, Raul Emrich ;
Popov, Todor A. ;
Sole, Dirceu .
JORNAL BRASILEIRO DE PNEUMOLOGIA, 2010, 36 (06) :693-699