Expanding Acquisition and Clutter Filter Dimensions for Improved Perfusion Sensitivity

被引:28
作者
Kim, MinWoo [1 ]
Abbey, Craig K. [2 ]
Hedhli, Jamila [3 ]
Dobrucki, Lawrence W. [3 ]
Insana, Michael F. [3 ]
机构
[1] Univ Illinois, Dept Elect & Comp Engn, Urbana, IL 61801 USA
[2] Univ Calif Santa Barbara, Dept Psychol & Brain Sci, Santa Barbara, CA 93106 USA
[3] Univ Illinois, Beckman Inst Adv Sci & Technol, Dept Bioengn, Urbana, IL 61801 USA
关键词
Adaptive eigenfilters; blood flow; higher order singular-value decomposition (HOSVD); ischemic hindlimb; power Doppler (PD); ultrasound; SINGULAR-VALUE DECOMPOSITION; ULTRASOUND; DOPPLER; DESIGN; STRATEGY;
D O I
10.1109/TUFFC.2017.2719942
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
A method is explored for increasing the sensitivity of power-Doppler imaging without contrast enhancement. We acquire 1-10 s of echo signals and arrange it into a 3-D spatiotemporal data array. An eigenfilter developed to preserve all three dimensions of the array yields power estimates for blood flow and perfusion that are well separated from tissue clutter. This method is applied at high frequency (24-MHz pulses) to a murine model of an ischemic hindlimb. We demonstrate enhancements to tissue perfusion maps in normal and ischemic tissues. The method can be applied to data from any ultrasonic instrument that provides beamformed RF echo data.
引用
收藏
页码:1429 / 1438
页数:10
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