Lignin modification improves fermentable sugar yields for biofuel production

被引：1001

作者：

Chen, Fang ^{[1
]}

Dixon, Richard A. ^{[1
]}

机构：

[1] Samuel Roberts Noble Fdn Inc, Div Plant Biol, Ardmore, OK 73401 USA

来源：

NATURE BIOTECHNOLOGY | 2007年 / 25卷 / 07期

基金：

美国能源部;

关键词：

DOWN-REGULATION; ALFALFA; FORAGE; ACID; SHIKIMATE; PLANTS; COA;

D O I：

10.1038/nbt1316

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Recalcitrance to saccharification is a major limitation for conversion of lignocellulosic biomass to ethanol. In stems of transgenic alfalfa lines independently downregulated in each of six lignin biosynthetic enzymes, recalcitrance to both acid pretreatment and enzymatic digestion is directly proportional to lignin content. Some transgenics yield nearly twice as much sugar from cell walls as wild-type plants. Lignin modification could bypass the need for acid pretreatment and thereby facilitate bioprocess consolidation.

引用

页码：759 / 761

页数：3

共 14 条

[1]

Badger P. C., 2002, Trends in new crops and new uses. Proceedings of the Fifth National Symposium, Atlanta, Georgia, USA, 10-13 November, 2001, P17

[2] Lignin biosynthesis [J].

Boerjan, W ;

Ralph, J ;

Baucher, M .

ANNUAL REVIEW OF PLANT BIOLOGY, 2003, 54 :519-546

[3] Multi-site genetic modulation of monolignol biosynthesis suggests new routes for formation of syringyl lignin and wall-bound ferulic acid in alfalfa (Medicago sativa L.) [J].

Chen, Fang ;

Reddy, Marry S. Srinivasa ;

Temple, Stephen ;

Jackson, Lisa ;

Shadle, Gail ;

Dixon, Richard A. .

PLANT JOURNAL, 2006, 48 (01) :113-124

[4] Variation of S/G ratio and lignin content in a Populus family influences the release of xylose by dilute acid hydrolysis [J].

Davison, Brian H. ;

Drescher, Sadie R. ;

Tuskan, Gerald A. ;

Davis, Mark F. ;

Nghiem, Nhuan P. .

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2006, 130 (1-3) :427-435

[5] Chemical composition and response to dilute-acid pretreatment and enzymatic saccharification of alfalfa, reed canarygrass, and switchgrass [J].

Dien, Bruce S. ;

Jung, Hans-Joachim G. ;

Vogel, Kenneth P. ;

Casler, Michael D. ;

Lamb, JoAnn F. S. ;

Iten, Loren ;

Mitchell, Robert B. ;

Sarath, Gautum .

BIOMASS & BIOENERGY, 2006, 30 (10) :880-891

[6] Improvement of in-rumen digestibility of alfalfa forage by genetic manipulation of lignin O-methyltransferases [J].

Guo, DG ;

Chen, F ;

Wheeler, J ;

Winder, J ;

Selman, S ;

Peterson, M ;

Dixon, RA .

TRANSGENIC RESEARCH, 2001, 10 (05) :457-464

[7] Ethanol from lignocellulosic biomass: techno-economic performance in short-, middle- and long-term [J].

Hamelinck, CN ;

van Hooijdonk, G ;

Faaij, APC .

BIOMASS & BIOENERGY, 2005, 28 (04) :384-410

[8] Purification, cloning, and properties of an acyltransferase controlling shikimate and quinate ester intermediates in phenylpropanoid metabolism [J].

Hoffmann, L ;

Maury, S ;

Martz, F ;

Geoffroy, P ;

Legrand, M .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (01) :95-103

[9] Improved paper pulp from plants with suppressed cinnamoyl-CoA reductase or cinnamyl alcohol dehydrogenase [J].

O'Connell, A ;

Holt, K ;

Piquemal, J ;

Grima-Pettenati, J ;

Boudet, A ;

Pollet, B ;

Lapierre, C ;

Petit-Conil, M ;

Schuch, W ;

Halpin, C .

TRANSGENIC RESEARCH, 2002, 11 (05) :495-503

[10] The path forward for biofuels and biomaterials [J].

Ragauskas, AJ ;

Williams, CK ;

Davison, BH ;

Britovsek, G ;

Cairney, J ;

Eckert, CA ;

Frederick, WJ ;

Hallett, JP ;

Leak, DJ ;

Liotta, CL ;

Mielenz, JR ;

Murphy, R ;

Templer, R ;

Tschaplinski, T .

SCIENCE, 2006, 311 (5760) :484-489

← 1 2 →