Skeletal complications of rheumatoid arthritis

被引：46

作者：

Heinlen, L. ^{[1
]}

Humphrey, M. B. ^{[1
,2
]}

机构：

[1] Univ Oklahoma, Hlth Sci Ctr, Oklahoma City, OK 73104 USA

[2] Vet Affairs Med Ctr, Oklahoma City, OK 73104 USA

来源：

OSTEOPOROSIS INTERNATIONAL | 2017年 / 28卷 / 10期

关键词：

Ankylosis; Bone erosions; Bone fracture; Osteoporosis; Rheumatoid arthritis; BONE-MINERAL DENSITY; QUALITY-OF-LIFE; MODIFYING ANTIRHEUMATIC DRUGS; NECROSIS-FACTOR INHIBITORS; TOTAL KNEE ARTHROPLASTY; RECENT-ONSET; DISEASE-ACTIVITY; JOINT REPLACEMENT; RADIOGRAPHIC PROGRESSION; INDUCED OSTEOPOROSIS;

D O I：

10.1007/s00198-017-4170-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rheumatoid arthritis (RA) is associated with local and systemic inflammation that induces many changes in the skeletal health. Locally, periarticular bone loss and juxta-articular bone erosions may occur while joint ankylosis, generalized bone loss, osteoporosis, and fractures may develop secondary to inflammation. The aim of this narrative review is to summarize the clinical evidence for abnormal skeletal health in RA, the effects of disease modifying anti-rheumatic drugs (DMARDS) on bone health, and the effects of drugs for the prevention or treatment of osteoporosis in the RA population.

引用

页码：2801 / 2812

页数：12

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