A Comparative Study of Laparoscopic versus Open Pancreaticoduodenectomy for Ampulla of Vater Carcinoma

被引：18

作者：

Yoo, Daegwang ^{[1
]}

Song, Ki Byung ^{[1
]}

Lee, Jong Woo ^{[1
]}

Hwang, Kyungyeon ^{[1
]}

Hong, Sarang ^{[1
]}

Shin, Dakyum ^{[1
]}

Hwang, Dae Wook ^{[1
]}

Lee, Jae Hoon ^{[1
]}

Lee, Woohyung ^{[1
]}

Kwon, Jaewoo ^{[1
]}

Park, Yejong ^{[1
]}

Jun, Eunsung ^{[1
]}

Kim, Song Cheol ^{[1
]}

机构：

[1] Univ Ulsan, Asan Med Ctr, Dept Surg, Div Hepatobiliary & Pancreat Surg,Coll Med, Seoul 05505, South Korea

来源：

JOURNAL OF CLINICAL MEDICINE | 2020年 / 9卷 / 07期

关键词：

ampulla of Vater; cancer; laparoscopy; pancreaticoduodenectomy; propensity score; PYLORUS-PRESERVING PANCREATICODUODENECTOMY; PROPENSITY-SCORE; DUCTAL ADENOCARCINOMA; COLON-CANCER; OUTCOMES; FEASIBILITY;

D O I：

10.3390/jcm9072214

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Several studies have compared laparoscopic pancreaticoduodenectomy (LPD) and open pancreaticoduodenectomy (OPD) in patients with periampullary carcinoma; however, only a few studies have made such a comparison on patients with ampulla of Vater cancer (AVC). We compared the perioperative and oncologic outcomes between LPD and OPD in patients with AVC using propensity-score-matched analysis. A total of 359 patients underwent PD due to AVC during the study period (76 LPD, 283 OPD). After propensity score matching, the LPD group showed significantly longer operation time than did the OPD group (400.2 vs. 344.6 min,p< 0.001). Nevertheless, the LPD group had fewer painkiller administrations (8.3 vs. 11.1,p< 0.049), fewer Grade II or more severe postoperative complications (15.9% vs. 34.8%,p= 0.012), and shorter postoperative hospital stays (13.7 vs. 17.3 days,p= 0.048), compared with the OPD group. There was no significant difference in recurrence-free outcomes and overall survival between the two groups (p= 0.754 and 0.768, respectively). Compared with OPD, LPD for AVC had comparative oncologic outcomes with less pain, less postoperative morbidity, and shorter hospital stays. LPD may serve as a promising alternative to OPD in patients with AVC.

引用

页码：1 / 10

页数：10

共 32 条

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