Lysine-Specific Demethylase 1 (LSD1) Inhibitors as Potential Treatment for Different Types of Cancers

被引：16
|
作者：
Abdel-Magid, Ahmed F. [1 ]
机构：
[1] Therachem Res Medilab India Pvt Ltd, Jaipur, Rajasthan, India
来源：
ACS MEDICINAL CHEMISTRY LETTERS | 2017年 / 8卷 / 11期
关键词：
D O I：
10.1021/acsmedchemlett.7b00426
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：1134 / 1135
页数：2
相关论文
共 50 条
  • [31] Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines
    Konovalov, Sergiy
    Garcia-Bassets, Ivan
    JOURNAL OF OVARIAN RESEARCH, 2013, 6
  • [32] Nonpeptidic Propargylamines as Inhibitors of Lysine Specific Demethylase 1 (LSD1) with Cellular Activity
    Schmitt, Martin L.
    Hauser, Alexander-Thomas
    Carlino, Luca
    Pippel, Martin
    Schulz-Fincke, Johannes
    Metzger, Eric
    Willmann, Dominica
    Yiu, Teresa
    Barton, Michelle
    Schuele, Roland
    Sippl, Wolfgang
    Jung, Manfred
    JOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (18) : 7334 - 7342
  • [33] Impact Of Ovariectomy On Aldosterone And Blood Pressure In Lysine-Specific Demethylase 1 (LSD1) Deficient Mice
    Stanton, Ana Maria
    Aljaibeji, Hayat
    Gholami, Shadi K.
    Parksook, Wasita
    Ding, Miao
    Gomez, Dulce H.
    Romero, Jose R.
    Pojoga, Luminita H.
    Williams, Gordon H.
    Adler, Gail K.
    HYPERTENSION, 2023, 80
  • [34] LYSINE-SPECIFIC HISTONE DEMETHYLASE 1 (LSD1) CONTRIBUTES TO THE MAINTENANCE OF GLIOBLASTOMA STEM CELL POPULATION
    Faletti, S.
    Osti, D.
    Richichi, C.
    Marangoni, I.
    Ceccacci, E.
    Minucci, S.
    Pelicci, G.
    NEURO-ONCOLOGY, 2018, 20 : 300 - 300
  • [35] Lysine-Specific Demethylase 1 (LSD1/KDM1A) Inhibition as a Target for Disease Modification in Myelofibrosis
    Gill, Harinder
    CELLS, 2022, 11 (13)
  • [36] Lysine specific demethylase 1 (Lsd1) is a potential biomarker and therapeutic target in retinoblastoma
    Ferdous, Salma
    Yeung, Aaron
    Rha, Jennifer
    Grossniklaus, Hans
    Nickerson, John M.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2020, 61 (07)
  • [37] A comprehensive comparative study on LSD1 in different cancers and tumor specific LSD1 inhibitors
    Dong, Jianshu
    Pervaiz, Waqar
    Tayyab, Bilal
    Li, Die
    Kang, Lei
    Zhang, Huimin
    Gong, Huimin
    Ma, Xinli
    Li, Jian
    Agboyibor, Clement
    Bi, Yuefeng
    Liu, Hongmin
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 240
  • [38] Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology
    Lim, Soyoung
    Janzer, Andreas
    Becker, Astrid
    Zimmer, Andreas
    Schuele, Roland
    Buettner, Reinhard
    Kirfel, Jutta
    CARCINOGENESIS, 2010, 31 (03) : 512 - 520
  • [39] QSAR Modeling, Molecular Docking and Molecular Dynamics Simulations Studies of Lysine-Specific Demethylase 1 (LSD1) Inhibitors as Anticancer Agents
    Abdizadeh, Rahman
    Heidarian, Esfandiar
    Hadizadeh, Farzin
    Abdizadeh, Tooba
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 21 (08) : 987 - 1018
  • [40] Evaluation of in vitro and in vivo efficacy of pharmacological lysine-specific demethylase 1 (LSD1) inhibitors in glioblastoma stem cell (GSC) models
    Stitzlein, Lea
    Gangadharan, Achintyan
    Grasse, Leslie
    Espejo, Alexsandra
    Singh, Melissa
    Lu, Yue
    Ezhilarasan, Ravesanker
    Gumin, Joy
    Sulman, Erik
    Lang, Frederick
    Chandra, Joya
    FASEB JOURNAL, 2022, 36
12345