Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer

被引：16

作者：

Stein, Gary S. ^{[1
]}

Zaidi, Sayyed K. ^{[1
]}

Stein, Janet L. ^{[1
]}

Lian, Jane B. ^{[1
]}

van Wijnen, Andre J. ^{[1
]}

Montecino, Martin ^{[2
]}

Young, Daniel W. ^{[3
]}

Javed, Amjad ^{[5
]}

Pratap, Jitesh ^{[1
]}

Choi, Je-Yong ^{[4
]}

Ali, Syed A. ^{[1
]}

Pande, Sandhya ^{[1
]}

Hassan, Mohammad Q. ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Dept Cell Biol, Worcester, MA 01655 USA

[2] Univ Concepcion, Fac Ciencias Biol, Dept Biol Mol, Concepcion 4079100, Chile

[3] Greenfield & Sacks PD, Wolf, Boston, MA 02210 USA

[4] Kyungpook Natl Univ, Sch Med, Skeletal Genome Res Ctr, Dept Biochem & Cell Biol, Taegu 700422, South Korea

[5] Univ Alabama Birmingham, Sch Dent, Inst Oral Hlth Res, Birmingham, AL USA

来源：

JOURNAL OF CELLULAR BIOCHEMISTRY | 2008年 / 104卷 / 06期

关键词：

nuclear microenvironments; epigenetic control; transcription; nuclear matrix; chromatin;

D O I：

10.1002/jcb.21813

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The regulatory machinery that governs genetic and epigenetic control of gene expression is compartmentalized in nuclear microenvironments. Temporal and spatial parameters of regulatory complex organization and assembly are functionally linked to biological control and are compromised with the onset and progression of tumorigenesis providing a novel platform for cancer diagnosis and treatment.

引用

页码：2016 / 2026

页数：11

共 50 条

[1] Nuclear microenvironments in biological control and cancer
Sayyed K. Zaidi
Daniel W. Young
Amjad Javed
Jitesh Pratap
Martin Montecino
Andre van Wijnen
Jane B. Lian
Janet L. Stein
Gary S. Stein
Nature Reviews Cancer, 2007, 7 : 454 - 463
[2] Nuclear microenvironments in biological control and cancer
Zaidi, Sayyed K.
Young, Daniel W.
Javed, Amjad
Pratap, Jitesh
Montecino, Martin
van Wijnen, Andre
Lian, Jane B.
Stein, Janet L.
Stein, Gary S.
NATURE REVIEWS CANCER, 2007, 7 (06) : 454 - 463
[3] Gene expression in nuclear microenvironments for biological control and cancer
Stein, Gary S.
CANCER BIOLOGY & THERAPY, 2007, 6 (11) : 1817 - 1821
[4] Organization of transcriptional regulatory machinery in nuclear microenvironments: Implications for biological control and cancer
Stein, G. S.
Lian, J. B.
van Wijnen, A. J.
Stein, J. L.
Javed, A.
Barnes, G.
Gerstenfeld, L.
Vradii, D.
Zaidi, S. K.
Pratap, J.
Young, D.
CANCER TREATMENT REVIEWS, 2006, 32 : S13 - S13
[5] Organization of transcriptional regulatory machinery in nuclear microenvironments: Implications for biological control and cancer
Stein, Gary S.
Lian, Jane B.
van Wijnen, Andre J.
Stein, Janet L.
Javed, Amjad
Montecino, Martin
Choi, Je-Yong
Vradii, Diana
Zaidi, Sayyed K.
Pratap, Jitesh
Young, Daniel
ADVANCES IN ENZYME REGULATION, VOL 47, 2007, 47 : 242 - +
[6] Architectural Genetic and Epigenetic Control of Regulatory Networks: Compartmentalizing Machinery for Transcription and Chromatin Remodeling in Nuclear Microenvironments
Stein, Gary S.
van Wijnen, Andre J.
Imbalzano, Anthony N.
Montecino, Martin
Zaidi, Sayyed K.
Lian, Jane B.
Nickerson, Jeffrey A.
Stein, Janet L.
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION, 2010, 20 (02): : 149 - 155
[7] Organization, Integration, and Assembly of Genetic and Epigenetic Regulatory Machinery in Nuclear Micro environments Implications for Biological Control in Cancer
Stein, Gary S.
Zaidi, Sayyed K.
Stein, Janet L.
Lian, Jane B.
van Wijnen, Andre J.
Montecino, Martin
Young, Daniel W.
Javed, Amjad
Pratap, Jitesh
Choi, Je-Yong
Ali, Syed A.
Pande, Sandhya
Hassan, Mohammad Q.
STEROID ENZYMES AND CANCER, 2009, 1155 : 4 - 14
[8] Beyond genetic control: epigenetic regulation
Jacobsen, S.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2012, 41 : 14 - 15
[9] Regulation and epigenetic control of transcription at the nuclear periphery
Ahmed, Sara
Brickner, Jason H.
TRENDS IN GENETICS, 2007, 23 (08) : 396 - 402
[10] Nuclear microenvironments and cancer
Stein, Gary S.
Davie, James R.
Knowlton, J. Randy
Zaidi, Sayyed K.
JOURNAL OF CELLULAR BIOCHEMISTRY, 2008, 104 (06) : 1949 - 1952

← 1 2 3 4 5 →