Properties of allyl alcohol-resistant mutants of Clostridium butyricum grown on glycerol

被引：6
作者：
AbbadAndaloussi, S
Amine, J
Gerard, P
Petitdemange, E
Petitdemange, H
机构：
[1] UNIV NANCY 1,LAB CHIM BIOL I,F-54506 VANDOEUVRE NANCY,FRANCE
[2] UNIV CHOUAIB DOUKKALI,BIOCHEM LAB,FAC SCI,EL JADIDA,MOROCCO
来源：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 1996年 / 62卷 / 09期
关键词：
D O I：
10.1128/AEM.62.9.3499-3501.1996
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Mutants of Clostridium butyricum E5 exhibiting resistance to allyl alcohol which produced the same quantities of 1,3-propanediol as the wild-type strain but more acetate than butyrate were isolated. The acetatebutyrate formation plays a major function in the regulation of the internal redox balance. Allyl alcohol resistance can be attributed not to the loss of 1,3-propanediol dehydrogenase but to a shift in the reductive properties of the enzyme. The data support the view that cellular regulation is modified to avoid intracellular accumulation of 3-hydroxypropionaldehyde.
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页码：3499 / 3501
页数：3
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