Aspartic acid as a highly efficient and nontoxic organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions

被引：11

作者：

Ghorbani-Choghamarani, A. ^{[1
]}

Hajjami, M. ^{[1
]}

Gholamian, F. ^{[1
]}

Azadi, G. ^{[1
]}

机构：

[1] Ilam Univ, Fac Sci, Dept Chem, Ilam, Iran

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 51卷 / 03期

关键词：

SILICA SULFURIC-ACID; REUSABLE CATALYST; 1,2,4,5-TETRASUBSTITUTED IMIDAZOLES; ANALGESIC ACTIVITY; OXIDATION; MILD; DERIVATIVES; SULFIDES; ALCOHOLS; SYSTEM;

D O I：

10.1134/S1070428015030100

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aspartic acid was found to be an efficient organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions. The remarkable advantages offered by this method are the inexpensive and green catalyst, mild reaction conditions, simple procedures, and excellent yield of products.

引用

收藏

页码：352 / 356

页数：5

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