Aspartic acid as a highly efficient and nontoxic organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions

被引：11
作者：
Ghorbani-Choghamarani, A. [1 ]
Hajjami, M. [1 ]
Gholamian, F. [1 ]
Azadi, G. [1 ]
机构：
[1] Ilam Univ, Fac Sci, Dept Chem, Ilam, Iran
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 51卷 / 03期
关键词：
SILICA SULFURIC-ACID; REUSABLE CATALYST; 1,2,4,5-TETRASUBSTITUTED IMIDAZOLES; ANALGESIC ACTIVITY; OXIDATION; MILD; DERIVATIVES; SULFIDES; ALCOHOLS; SYSTEM;
D O I：
10.1134/S1070428015030100
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Aspartic acid was found to be an efficient organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions. The remarkable advantages offered by this method are the inexpensive and green catalyst, mild reaction conditions, simple procedures, and excellent yield of products.
引用
收藏
页码：352 / 356
页数：5
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共 39 条
  • [1] One-pot synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles by zinc oxide as efficient and reusable catalyst
    Bahrami, Kiumars
    Khodaei, Mohammad M.
    Nejati, Akbar
    [J]. MONATSHEFTE FUR CHEMIE, 2011, 142 (02): : 159 - 162
  • [2] One-Pot Synthesis of 2,4,5-Trisubstituted Imidazoles Using MoO3/SiO2, an Efficient and Recyclable Catalyst
    Bhosale, Sidhanath V.
    Kalyankar, Mohan B.
    Nalage, Santosh V.
    Bhosale, Dattatry S.
    Pandhare, Swati L.
    Kotbagi, Trupti V.
    Umbarkar, Shubhangi B.
    Dongare, Mohan K.
    [J]. SYNTHETIC COMMUNICATIONS, 2011, 41 (05) : 762 - 769
  • [3] CIMETIDINE - NON-THIOUREA H2-RECEPTOR ANTAGONIST
    BRIMBLECOMBE, RW
    DUNCAN, WAM
    DURANT, GJ
    EMMETT, JC
    GANELLIN, CR
    PARSONS, ME
    [J]. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 1975, 3 (02) : 86 - 92
  • [4] METRONIDAZOLE IN ANAEROBIC INFECTIONS - REVIEW OF ITS ACTIVITY, PHARMACOKINETICS AND THERAPEUTIC USE
    BROGDEN, RN
    HEEL, RC
    SPEIGHT, TM
    AVERY, GS
    [J]. DRUGS, 1978, 16 (05) : 387 - 417
  • [5] SYNTHESIS OF PYROGLUTAMYLHISTIDYLPROLINEAMIDE BY CLASSICAL AND SOLID PHASE METHODS
    FLOURET, G
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1970, 13 (05) : 843 - &
  • [6] Synthesis of substituted imidazoles via organocatalysis
    Frantz, DE
    Morency, L
    Soheili, A
    Murry, JA
    Grabowski, EJJ
    Tillyer, RD
    [J]. ORGANIC LETTERS, 2004, 6 (05) : 843 - 846
  • [7] Polyvinylpolypyrrolidone-Supported Hydrogen Peroxide (PVP-H2O2), Silica Sulfuric Acid and Catalytic Amounts of Ammonium Bromide as Green, Mild and Metal-Free Oxidizing Media for the Efficient Oxidation of Alcohols and Sulfides
    Ghorbani-Choghamarani, A.
    Azadi, G.
    [J]. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2011, 8 (04) : 1082 - 1090
  • [8] Catalytic Oxidation of Sulfides to Sulfoxides Using Aluminium Hydrogen Sulfate, Sodium Nitrite and Catalytic Amounts of Metal Bromide
    Ghorbani-Choghamarani, A.
    Zeinivand, J.
    [J]. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2010, 7 (01) : 190 - 194
  • [9] Ghorbani-Choghamarani A., 2012, J SERB CHEM SOC, V77, P173
  • [10] Green and One-Pot Three-Component Synthesis of 2,3-Dihydroquinazolin-4(1H)-Ones Promoted by Citric Acid as Recoverable Catalyst in Water
    Ghorbani-Choghamarani, Arash
    Taghipour, Tahereh
    [J]. LETTERS IN ORGANIC CHEMISTRY, 2011, 8 (07) : 470 - 476
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