68Ga-Exendin-4 PET/CT Differentiates Insulinoma From Accessory Spleen in a Patient Presenting Indeterminate MRI and 68Ga-DOTATATE PET/CT Findings

被引：3
作者：
Pang, Yizhen [1 ,2 ]
Meng, Tinghua [1 ,2 ]
Shang, Qihang [1 ,2 ]
Chen, Zheng [3 ,4 ]
Chen, Haojun [1 ,2 ]
机构：
[1] Xiamen Univ, Affiliated Hosp 1, Dept Nucl Med, Xiamen Canc Hosp, Xiamen, Peoples R China
[2] Xiamen Univ, Affiliated Hosp 1, Minnan PET Ctr, Xiamen Canc Hosp, Xiamen, Peoples R China
[3] Xiamen Univ, Affiliated Hosp 1, Dept Endocrinol & Diabet, Xiamen Diabet Inst, Xiamen, Peoples R China
[4] Xiamen Univ, Affiliated Hosp 1, Xiamen Clin Med Ctr Endocrine & Metab Dis, Xiamen, Peoples R China
来源：
CLINICAL NUCLEAR MEDICINE | 2022年 / 47卷 / 03期
关键词：
Ga-68-exendin-4; Ga-68-DOTATATE; PET/CT; accessory spleen; insulinoma; NEUROENDOCRINE TUMOR;
D O I：
10.1097/RLU.0000000000003895
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
ABSTRACT: A 55-year-old woman with endogenous hyperinsulinemia hypoglycemia was clinically diagnosed with insulinoma. Contrast-enhanced MRI revealed an inconclusive hypointense lesion in the pancreatic tail, and the enhancement pattern does not support the diagnosis of insulinoma. 68Ga-DOTATATE PET/CT showed intense radioactivity in this nodule, similar to the radioactivity of the adjacent spleen. Therefore, the diagnosis of accessory spleen cannot be excluded. Follow-up with 68Ga-exendin-4 PET/CT also showed intense uptake in this nodule, but no significant uptake in the spleen was observed at this time. Therefore, the insulinoma was unmasked from the spleen, excluding the diagnosis of accessory spleen, and allowing curative surgery. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码：265 / 267
页数：3
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