A site's fundamental resonance frequency (f(0)), or its reciprocal, the fundamental period (T-0), is a critical parameter in seismic studies due to its proven ability to aid in predicting local site effects (i.e., frequency-dependent amplification of seismic waves). The horizontal-to-vertical spectral ratio (HVSR) method is a popular nonintrusive technique that can be used to estimate f(0) in a time-efficient and cost-effective manner. Although it is becoming more and more common to perform several HVSR measurements to investigate spatial variability in f(0) across a site, the measurements often are irregularly spaced due to access and/or budget restrictions. This has the potential of introducing significant bias when attempting to estimate a single, representative f(0) across an area of interest. To address this problem, we propose the use of Voronoi tessellations to obtain an unbiased, statistical representation of f(0) or T-0 from spatially distributed HVSR measurements. After area boundaries are set, Voronoi tessellation yields unique spatial estimates in a relatively simple and fast manner, which makes it appealing for standardization. To accommodate the current state of practice in HVSR processing, two distinct statistical approaches were presented. The choice of which approach to use is governed by whether the f(0) values at each HVSR location are reported deterministically (i.e., as single f(0) values without variance) or statistically (i.e., as f(0) values with associated variance). Three example applications were presented to illustrate potential uses. The first application demonstrated the effectiveness of the adopted approach in correcting for bias introduced by irregular spatial sampling. The second application illustrated how better-informed seismic site classifications can be made using a statistical representation of T-0. The third application compared the relative degree of spatial variability in f(0) at two downhole array sites to assess the applicability of performing one-dimensional (1D) ground response analyses. (C) 2021 American Society of Civil Engineers.