Novel Enzymatic Synthesis of 3-hydroxybutyric Add Oligomers with Inserted Lactobionic Acid Moieties

被引：0

作者：

Kakasi-Zsurka, Sandor ^{[1
,3
]}

Todea, Anamaria ^{[1
]}

But, Andrada ^{[1
]}

Paul, Cristina ^{[1
]}

Boeriu, Carmen ^{[2
,4
]}

Nagy, Lajos ^{[3
]}

Davidescu, Corneliu Mircea ^{[1
]}

Peter, Francisc ^{[1
]}

机构：

[1] Univ Politehn Timisoara, Fac Ind Chem & Environm Engn, Timisoara 30001, Romania

[2] Wageningen UR Food & Biobased Res, Div Biobased Prod, Wageningen, Netherlands

[3] Univ Debrecen, Dept Appl Chem, H-4010 Debrecen, Hungary

[4] Aurel Vlaicu Univ Arad, Dept Chem & Biol Sci, Arad, Romania

来源：

REVISTA DE CHIMIE | 2011年 / 62卷 / 10期

关键词：

lactobionic acid; 3-hydroxybutyric acid; copolymers; lipase; biocatalysis; POLYMER;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3-Hydroxybutyric acid and lactobionic acid yielded linear and cyclic oligomers in a lipase-catalyzed condensation polymerization reaction, performed at 80 degrees C in bulk and organic solvent systems. Novozyme 435 was the most efficient biocatalyst, and a mixture of t-butanol and dimethylsulfoxide in 80:20 (v/v) ratio provided the highest copolymer conversions. The highest degree of polymerization reached 7 in case of copolymers with inserted lactobionic acid moiety and 11 for the 3-hydroxybutyric acid homopolymer byproduct.

引用

页码：958 / 963

页数：6

共 18 条

[1] Recent developments in enzyme-catalyzed ring-opening polymerization
Albertsson, Ann-Christine
Srivastava, Rajiv K.
[J]. ADVANCED DRUG DELIVERY REVIEWS, 2008, 60 (09) : 1077 - 1093
[2] Bornscheuer UT, 2006, HYDROLASES IN ORGANIC SYNTHESIS: REGIO- AND STEREOSELECTIVE BIOTRANSFORMATIONS, 2ND EDITION, P1
[3] A novel PHB depolymerase from a thermophilic Streptomyces sp.
Calabia, BP
Tokiwa, Y
[J]. BIOTECHNOLOGY LETTERS, 2006, 28 (06) : 383 - 388
[4] Enzymatic and chemoenzymatic approaches to synthesis of sugar based polymer and hydrogels
Chen, X
Martin, BD
Neubauer, TK
Linhardt, RJ
Dordick, JS
Rethwisch, DG
[J]. CARBOHYDRATE POLYMERS, 1995, 28 (01) : 15 - 21
[5] Enzyme-catalysis breathes new life into polyester condensation polymerizations
Gross, Richard A.
Ganesh, Manoj
Lu, Wenhua
[J]. TRENDS IN BIOTECHNOLOGY, 2010, 28 (08) : 435 - 443
[6] Synthesis of highly functionalized oligo- and copolyesters from a carbohydrate lactone
Haider, Anita F.
Williams, Charlotte K.
[J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2008, 46 (08) : 2891 - 2896
[7] Polymer synthesis by enzymatic catalysis
Kadokawa, Jun-ichi
Kobayashi, Shiro
[J]. CURRENT OPINION IN CHEMICAL BIOLOGY, 2010, 14 (02) : 145 - 153
[8] KAKASI-ZSURKA S., 2009, ANN W U TIMISOARA C, V18, P29
[9] KAKASIZSURKA S, 2008, ANN W U TIMISOARA C, V17, P67
[10] Enzymatic polymerization
Kobayashi, S
Uyama, H
Kimura, S
[J]. CHEMICAL REVIEWS, 2001, 101 (12) : 3793 - 3818

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