Novel Types of Staphylococcal Cassette Chromosome mec Elements Identified in Clonal Complex 398 Methicillin-Resistant Staphylococcus aureus Strains

被引：121

作者：

Li, Shanshuang ^{[1
,2
]}

Skov, Robert Leo ^{[3
]}

Han, Xiao ^{[2
]}

Larsen, Anders Rhod ^{[3
]}

Larsen, Jesper ^{[3
]}

Sorum, Marit ^{[3
]}

Wulf, Mireille ^{[5
]}

Voss, Andreas ^{[4
,6
,7
]}

Hiramatsu, Keiichi ^{[1
,2
]}

Ito, Teruyo ^{[1
,2
]}

机构：

[1] Juntendo Univ, Sch Med, Dept Bacteriol, Tokyo 113, Japan

[2] Juntendo Univ, Grad Sch Med, Dept Infect Control Sci, Tokyo 113, Japan

[3] Statens Serum Inst, Dept Microbiol Surveillance & Res, DK-2300 Copenhagen, Denmark

[4] PAMM, Lab Med Microbiol, Veldhoven, Netherlands

[5] Catharina Hosp, Eindhoven, Netherlands

[6] Radboud Univ Nijmegen Med Ctr RUNMC, Nijmegen, Netherlands

[7] Canisius Wilhelmina Hosp, Nijmegen, Netherlands

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 06期

关键词：

PIG FARMERS; ST398; DIVERSITY; HUMANS; GENOME; SCCMEC; SWINE;

D O I：

10.1128/AAC.01475-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The structures of staphylococcal cassette chromosome mec (SCCmec) elements carried by 31 clonal complex 398 (CC398) methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from the participants at a conference were analyzed. The SCCmecs were classified into novel types, namely, IX, X, V(5C2&5) subtype c, and IVa. Type V(5C2&5) subtype c, IX, and X SCCmecs carried genes conferring resistance to metals. The structures of SCCmecs from CC398 strains were distinct from those normally found in humans, adding to the evidence that humans are not the original host for CC398.

引用

页码：3046 / 3050

页数：5

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