Flow Synthesis of Heterocycles

被引:3
作者
Movsisyan, Marine [1 ]
Moens, Matthias M. A. [1 ]
Stevens, Christian V. [1 ]
机构
[1] Univ Ghent, SynBioC Res Grp, Dept Sustainable Organ Chem & Technol, Fac Biosci Engn, Ghent, Belgium
来源
HETEROCYCLIC CHEMISTRY IN THE 21ST CENTURY: A TRIBUTE TO ALAN KATRITZKY | 2016年 / 119卷
关键词
Continuous flow; Heterocycles; Microreactor; Sustainable processes; Telescoping; IN-TUBE REACTOR; CONTINUOUS CRYSTALLIZATION; MULTISTEP SYNTHESIS; ORGANIC-SYNTHESIS; MIXED-SUSPENSION; MICROREACTORS; CHEMISTRY; TECHNOLOGY; NANOPARTICLES; GENERATION;
D O I
10.1016/bs.aihch.2015.10.006
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Continuous microreactor systems have gained a lot of interest in the field of organic synthesis as these possess enhanced mass and heat transfer properties. Microreactor technology also offers a contemporary way of conducting chemical reactions in a more sustainable fashion due to the miniaturization and increased safety, and also in a technically improved manner due to intensified process efficiency. Recent developments in this area related to the synthesis of heterocyclic compounds are recorded in this chapter. Also, telescoping, in which several subsequent reaction steps (with or without purification) can be achieved by connecting different reactors to each other, is covered.
引用
收藏
页码:25 / 55
页数:31
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