Usefulness of therapeutic drug monitoring in estimating the duration of dalbavancin optimal target attainment in staphylococcal osteoarticular infections: a proof-of-concept

被引：29

作者：

Cojutti, Pier Giorgio ^{[1
]}

Rinaldi, Matteo ^{[2
,3
]}

Gatti, Milo ^{[1
,2
]}

Tedeschi, Sara ^{[2
,3
]}

Viale, Pierluigi ^{[2
,3
]}

Pea, Federico ^{[1
,2
]}

机构：

[1] IRCCS Azienda Osped Univ Bologna, SSD Clin Pharmacol, Bologna, Italy

[2] Univ Bologna, Dept Med & Surg Sci, Alma Mater Studiorum, Bologna, Italy

[3] IRCCS Azienda Osped Univ Bologna, Infect Dis Unit, Bologna, Italy

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2021年 / 58卷 / 05期

关键词：

Therapeutic drug monitoring; TDM; Dalbavancin; Osteoarticular infection; Staphylococci; Duration of treatment; AUREUS; BONE;

D O I：

10.1016/j.ijantimicag.2021.106445

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Dalbavancin is increasingly used for the treatment of staphylococcal osteoarticular infections (OIs). Some population pharmacokinetic studies suggest that a regimen of two 1500 mg doses 1 week apart could ensure effective treatment for several weeks. Here we aim to provide clinicians with a proof-of-concept of the potential role that therapeutic drug monitoring may have in giving real-time feedback of the estimated duration of optimal treatment of staphylococcal OIs with dalbavancin in each single patient. (c) 2021 Elsevier Ltd and International Society of Antimicrobial Chemotherapy. All rights reserved.

引用

页数：3

共 4 条

[1] Innovation in microsampling for therapeutic drug monitoring of gentamicin in neonates: a proof-of-concept study
Parker, Suzanne L.
Irwin, Adam D.
Hosking, Francine
August, Deanne
Schoenmaker, Brittany
Pandey, Saurabh
Wallis, Steven C.
Lipman, Jeffrey
Roberts, Jason A.
Davies, Mark W.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2022, 59 (02)
[2] Implementation and validation of a Bayesian method for accurately forecasting duration of optimal pharmacodynamic target attainment with dalbavancin during long-term use for subacute and chronic staphylococcal infections
Cojutti, Pier Giorgio
Gatti, Milo
Punt, Nieko
Dousa, Jiri
Zamparini, Eleonora
Tedeschi, Sara
Viale, Pierluigi
Pea, Federico
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2024, 63 (01)
[3] Therapeutic drug monitoring of inhaled therapies in hair of patients with asthma: a proof-of-concept study
Lamy, E.
Salvator, H.
Naline, E.
Couderc, Lj
Devillier, P.
Grassin-Delyle, S.
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2019, 33 : 34 - 34
[4] Therapeutic drug monitoring of antiretroviral drugs at home using dried blood spots: a proof-of-concept study
Kromdijk, Wiete
Mulder, Jan W.
Smit, Patrick M.
ter Heine, Rob
Beijnen, Jos H.
Huitema, Alwin D. R.
ANTIVIRAL THERAPY, 2013, 18 (06) : 821 - 825

← 1 →