Two New Triterpenoid Glycosides from the Roots of Rosa cymosa Tratt.

被引：6

作者：

Ma, Guo-Xu ^{[1
,2
]}

Huang, Xiao-Yan ^{[3
]}

Dai, Hua-Nian ^{[3
]}

Zhong, Xiao-Qing ^{[4
]}

Zhou, Yan-Lin ^{[4
]}

Su, Zuo-Lin ^{[5
]}

He, Ying-Zi ^{[3
]}

Yang, Jun-Shan ^{[1
,2
]}

Yuan, Jing-Quan ^{[3
,6
]}

Xu, Xu-Dong ^{[1
,2
]}

机构：

[1] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China

[2] Peking Union Med Coll, Beijing 100193, Peoples R China

[3] Guangxi Teachers Educ Univ, Coll Chem & Mat Sci, Nanning 530001, Peoples R China

[4] Guilin Sanjin Pharmaceut Co Ltd, Guilin 541004, Peoples R China

[5] Guangxi Lingfeng Pharmaceut Co Ltd, Hezhou 542800, Peoples R China

[6] Guangxi Inst Med Plant, Nanning 530023, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2016年 / 99卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Rosa cymosa Tratt; Triterpenoid glycosides; Anti-inflammatory activity; Ursane triterpenes; Oleanane triterpenes; SAPONINS; LEAVES;

D O I：

10.1002/hlca.201500548

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new triterpenoid glycosides, 3,19,23-trihydroxy-2-oxo-12-ursen-28-O--d-glucopyranoside (1) and 3,19,23-trihydroxy-2-oxoolean-12-en-28-O--d-glucopyranoside (2) as well as three known compounds, 2,3,19-trihydroxyolean-12-en-28-O--d-glucopyranoside (3), 2,3,19,23-tetrahydroxy-12-ursen-28-O--d-glucopyranoside (4), and 2,3,19,23-tetrahydroxyurs-12-en-28-oic acid (5) were isolated from 75% EtOH extract of Rosa cymosa. Their structures were elucidated by extensive spectroscopic methods. All the isolated compounds displayed moderate inhibitory activity against LPS-induced NO production in macrophages.

引用

页码：482 / 486

页数：5

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