99mTc-PSMA SPECT in Prostate Cancer

被引：0
作者：
Omar, Yehia [1 ]
Taha, Noha M. [2 ]
机构：
[1] Misr Radiol Ctr, Cairo, Egypt
[2] Ain Shams Univ, Cairo, Egypt
来源：
CLINICAL AND TRANSLATIONAL IMAGING | 2022年 / 10卷 / 06期
关键词：
Prostate cancer; PSMA; SPECT; Tc-99m; PET; PSMA-SPECT/CT; PET; DIAGNOSIS; LIGAND;
D O I：
10.1007/s40336-022-00498-5
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Prostate cancer is the most common male cancer and is a leading cause for cancer-associated death in men worldwide. PSMA-PET/CT imaging is emerging as a standard of care in prostate cancer imaging and has been included in recent NCCN guidelines, yet its wide access is still an issue because (68)Gallium labelled PSMA tracer needs "high financial costs" to purchase (68)Gallium generator and labelling equipment. In addition, the (18)Fluorinated labelled PSMA tracer, needs the PET/CT site to be "in close vicinity" to a cyclotron supplying the tracer. On the contrary, Technetium generators and SPECT machines are widely available in healthcare facilities throughout the world due to their lower cost. This pictorial essay highlights our initial experience using Tc-99m-PSMA SPECT, which supports further investigation as it is showing encouraging results for prostate cancer imaging and could also play a role in pre-radioligand therapy assessment in the future.
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收藏
页码：677 / 685
页数：9
相关论文
共 22 条
[1]   The Theranostic PSMA Ligand PSMA-617 in the Diagnosis of Prostate Cancer by PET/CT: Biodistribution in Humans, Radiation Dosimetry, and First Evaluation of Tumor Lesions [J].
Afshar-Oromieh, Ali ;
Hetzheim, Henrik ;
Kratochwil, Clemens ;
Benesova, Martina ;
Eder, Matthias ;
Neels, Oliver C. ;
Eisenhut, Michael ;
Kuebler, Wolfgang ;
Holland-Letz, Tim ;
Giesel, Frederik L. ;
Mier, Walter ;
Kopka, Klaus ;
Haberkorn, Uwe .
JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (11) :1697-1705
[2]   Comparison of PET imaging with a 68Ga-labelled PSMA ligand and 18F-choline-based PET/CT for the diagnosis of recurrent prostate cancer [J].
Afshar-Oromieh, Ali ;
Zechmann, Christian M. ;
Malcher, Anna ;
Eder, Matthias ;
Eisenhut, Michael ;
Linhart, Heinz G. ;
Holland-Letz, Tim ;
Hadaschik, Boris A. ;
Giesel, Frederik L. ;
Debus, Juergen ;
Haberkorn, Uwe .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2014, 41 (01) :11-20
[3]  
Al Saqri, 2020, INTERESTING MEDICAL, V5, P1744
[4]  
Albalooshi Batool, 2020, Asia Ocean J Nucl Med Biol, V8, P1, DOI 10.22038/aojnmb.2019.43943.1293
[5]   Diagnostic Performance of PET Imaging Using Different Radiopharmaceuticals in Prostate Cancer According to Published Meta-Analyses [J].
Annunziata, Salvatore ;
Pizzuto, Daniele Antonio ;
Treglia, Giorgio .
CANCERS, 2020, 12 (08) :1-14
[6]  
[Anonymous], 2024, SEER Cancer Stat Facts
[7]   Multiphasic 68Ga-PSMA PET/CT in the Detection of Early Recurrence in Prostate Cancer Patients with a PSA Level of Less Than 1 ng/mL: A Prospective Study of 135 Patients [J].
Beheshti, Mohsen ;
Manafi-Farid, Reyhaneh ;
Geinitz, Hans ;
Vali, Reza ;
Loidl, Wolfgang ;
Mottaghy, Felix M. ;
Langsteger, Werner .
JOURNAL OF NUCLEAR MEDICINE, 2020, 61 (10) :1484-1490
[8]   68Ga-PSMA I&T PET/CT for primary staging of prostate cancer [J].
Cytawa, Wojciech ;
Seitz, Anna Katharina ;
Kircher, Stefan ;
Fukushima, Kazuhito ;
Tran-Gia, Johannes ;
Schirbel, Andreas ;
Bandurski, Tomasz ;
Lass, Piotr ;
Krebs, Markus ;
Polom, Wojciech ;
Matuszewski, Marcin ;
Wester, Hans-Juergen ;
Buck, Andreas K. ;
Kuebler, Hubert ;
Lapa, Constantin .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2020, 47 (01) :168-177
[9]   Rapid Modulation of PSMA Expression by Androgen Deprivation: Serial 68Ga-PSMA-11 PET in Men with Hormone-Sensitive and Castrate-Resistant Prostate Cancer Commencing Androgen Blockade [J].
Emmett, Louise ;
Yin, Charlotte ;
Crumbaker, Megan ;
Hruby, George ;
Kneebone, Andrew ;
Epstein, Richard ;
Quoc Nguyen ;
Hickey, Adam ;
Ihsheish, Noah ;
O'Neill, Gordon ;
Horvath, Lisa ;
Chalasani, Venu ;
Stricker, Phillip ;
Joshua, Anthony M. .
JOURNAL OF NUCLEAR MEDICINE, 2019, 60 (07) :950-954
[10]  
Fornell, 2008, NUCL IMAGING, V03
123