Aggressive Soft Tissue Infections

被引：17

作者：

Garcia, Nicole M. ^{[1
]}

Cai, Jenny ^{[1
]}

机构：

[1] East Carolina Univ, Div Trauma & Acute Care Surg, Dept Surg, Brody Sch Med, 600 Moye Blvd, Greenville, NC 27858 USA

来源：

SURGICAL CLINICS OF NORTH AMERICA | 2018年 / 98卷 / 05期

关键词：

Necrotizing fasciitis; Soft tissue infection; Sepsis; Gas gangrene; DISTINGUISHING NECROTIZING FASCIITIS; FOURNIERS GANGRENE; HYPERBARIC-OXYGEN; IMMUNOGLOBULIN-G; RISK-FACTORS; MANAGEMENT; MORTALITY; DIAGNOSIS; THERAPY; MICROBIOLOGY;

D O I：

10.1016/j.suc.2018.05.001

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Necrotizing soft tissue infections (NSTIs) are characterized by rapidly progressive infection that causes tissue necrosis with associated sepsis and multisystem organ failure. A rapid diagnosis is essential to decreasing the morbidity and mortality of NSTIs. There must be a high index of suspicion based on history and physical examination. There are no adjunct laboratory values or imaging that have high sensitivity and specificity in the diagnosis of NSTI. The treatment involves emergent, radical surgical debridement of involved tissues and broad-spectrum antibiotics. Follow-up should include close monitoring of the wound and repeat debridements in the operating room.

引用

页码：1097 / 1108

页数：12

共 53 条

[1] Reverse Epidemiology of Traditional Cardiovascular Risk Factors in the Geriatric Population [J].

Ahmadi, Seyed-Foad ;

Streja, Elani ;

Zahmatkesh, Golara ;

Streja, Dan ;

Kashyap, Moti ;

Moradi, Hamid ;

Molnar, Miklos Z. ;

Reddy, Uttam ;

Amin, Alpesh N. ;

Kovesdy, Csaba P. ;

Kalantar-Zadeh, Kamyar .

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2015, 16 (11) :933-939

[2] Predictors of mortality and limb loss in necrotizing soft tissue infections [J].

Anaya, DA ;

McMahon, K ;

Nathens, AB ;

Sullivan, SR ;

Foy, H ;

Bulger, E .

ARCHIVES OF SURGERY, 2005, 140 (02) :151-157

[3] Massive infectious soft-tissue injury: Diagnosis and management of necrotizing fasciitis and purpura fulminans [J].

Andreasen, TJ ;

Green, SD ;

Childers, BJ .

PLASTIC AND RECONSTRUCTIVE SURGERY, 2001, 107 (04) :1025-1034

[4]

[Anonymous], 1994, MMWR Morbidity and mortality weekly report, V43, P401

[5] Antimicrobial Susceptibilities of Aeromonas Strains Isolated from Clinical and Environmental Sources to 26 Antimicrobial Agents [J].

Aravena-Roman, Max ;

Inglis, Timothy J. J. ;

Henderson, Barbara ;

Riley, Thomas V. ;

Chang, Barbara J. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (02) :1110-1112

[6] Necrotizing fasciitis of the head and neck: Role of CT in diagnosis and management [J].

Becker, M ;

Zbaren, P ;

Hermans, R ;

Becker, CD ;

Marchal, F ;

Kurt, AM ;

Marre, S ;

Rufenacht, DA ;

Terrier, F .

RADIOLOGY, 1997, 202 (02) :471-476

[7]

Bilton BD, 1998, AM SURGEON, V64, P397

[8] Necrotizing fasciitis in children:: diagnostic and therapeutic aspects [J].

Bingoel-Kologlu, Meltern ;

Yidiz, Rahsan Varguen ;

Alper, Bilal ;

Yagmurlu, Aydin ;

Ciftci, Ergin ;

Goekcora, Ismail Haluk ;

Ince, Erdal ;

Emiroglu, Murat ;

Dindar, Hueseyin .

JOURNAL OF PEDIATRIC SURGERY, 2007, 42 (11) :1892-1897

[9] Submandibular space infection: a potentially lethal infection [J].

Boscolo-Rizzo, Paolo ;

Da Mosto, Maria Cristina .

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2009, 13 (03) :327-333

[10] Necrotizing soft tissue infections [J].

Cainzos, Miguel ;

Gonzalez-Rodriguez, Francisco J. .

CURRENT OPINION IN CRITICAL CARE, 2007, 13 (04) :433-439

← 1 2 3 4 5 6 →