GENETICS Mitochondrial DNA in evolution and disease

被引：72

作者：

Wallace, Douglas C. ^{[1
]}

机构：

[1] Childrens Hosp Philadelphia, Ctr Mitochondrial & Epigenom, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept pathol & Lab Med, Philadelphia, PA 19104 USA

来源：

NATURE | 2016年 / 535卷 / 7613期

关键词：

D O I：

10.1038/nature18902

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cellular organelles called mitochondria contain their own DNA. The discovery that variation in mitochondrial DNA alters physiology and lifespan in mice has implications for evolutionary biology and the origins of disease. See Letter p.561

引用

页码：498 / 500

页数：3

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