Bio-based thermostable, biodegradable and biocompatible hyperbranched polyurethane/Ag nanocomposites with antimicrobial activity

被引：61

作者：

Deka, Harekrishna ^{[1
]}

Karak, Niranjan ^{[1
]}

Kalita, Ranjan D. ^{[2
]}

Buragohain, Alak K. ^{[2
]}

机构：

[1] Tezpur Univ, Dept Chem Sci, Adv Polymer & Nanomat Lab, Tezpur 784028, India

[2] Tezpur Univ, Dept Mol Biol & Biotechnol, Tezpur 784028, India

来源：

POLYMER DEGRADATION AND STABILITY | 2010年 / 95卷 / 09期

关键词：

Antimicrobial; Biodegradation; Thermostability; Biocompatibility; Polyurethane nanocomposites; SILVER NANOPARTICLES; MECHANICAL-PROPERTIES; POLYACRYLAMIDE; TOXICITY; IONS;

D O I：

10.1016/j.polymdegradstab.2010.06.017

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The enhanced thermal and antimicrobial activity of silver nanoparticles prompts their uses in many medical devices. Mesua ferrea L seed oil based antimicrobial biocompatible hyperbranched and linear polyurethane/Ag nanocomposites have been prepared in dimethylformamide without using any extra reducing agent. Formation of the stable and well-dispersed Ag nanoparticles was confirmed by ultra violet, X-ray diffractometeric, transmission electron microscopic and Fourier transform infra-red spectroscopic analyses. The enhancement of properties like thermal stability by (46-53)degrees C and 42 degrees C, tensile strength to similar to 170% and similar to 180% for hyperbranched and linear polyurethanes respectively was observed by the formation of nanocomposites. The cytocompatibility test based on the inhibition of RBC hemolysis showed that the materials lack cytotoxicity. The nanocomposites showed biodegradability as conferred from the bacterial degradation. Dose dependent excellent antibacterial activity of the nanocomposites against Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli) bacteria and anti-fouling activity against Candida albicans was observed. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：1509 / 1517

页数：9

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